Simple Summary Tumor angiogenesis is one of the most critical steps in the progression of
cancer. Owing to its fundamental role in tumor growth and metastasis, tumor angiogenesis is …

Highlights•Chemotherapy-induced neutropenia can lead to poor clinical outcomes.•CIN can
lead to infections, hospitalizations, mortality, and lower chemotherapy dose intensity.•G-CSF …

Neutrophils, the most copious leukocytes in human blood, play a critical role in
tumorigenesis, cancer progression, and immune suppression. Recently, neutrophils have …

Sepsis is defined as life-threatening organ dysfunction caused by a dysregulated host
response to infection. Common causes include gram-negative and gram-positive bacteria as …

Efbemalenograstim alfa (Ryzneuta®) is a subcutaneously administered recombinant fusion
protein that is being developed by Evive Biotech for the management of chemotherapy …

The stimulator of interferon genes (STING) protein is an important and promising innate
immune target for tumor therapy. However, the instability of the agonists of STING and their …

Chemokines are mainly studied for their local function in the control of leukocyte
extravasation in homeostatic and inflammatory conditions. However, they have additional …

Background Ulcerative colitis (UC) progression is driven by the activation of immune cells
that release pro-inflammatory mediators to disrupt intestinal epithelial barrier integrity. This …

Background and aims: Granulocyte colony-stimulating factor (G-CSF) has been proposed as
a therapeutic option for patients with ACLF, however clinical outcomes are controversial. We …

Tocotrienols have powerful radioprotective properties in multiple organ systems and are
promising candidates for development as clinically effective radiation countermeasures. To …