Uterine fibroids: current perspectives

AT Khan, M Shehmar, JK Gupta - International journal of women's …, 2014 - Taylor & Francis
Uterine fibroids are a major cause of morbidity in women of a reproductive age (and
sometimes even after menopause). There are several factors that are attributed to underlie …

Hyperthermia-triggered drug delivery from temperature-sensitive liposomes using MRI-guided high intensity focused ultrasound

H Grüll, S Langereis - Journal of Controlled Release, 2012 - Elsevier
In the continuous search for cancer therapies with a higher therapeutic window, localized
temperature-induced drug delivery may offer a minimal invasive treatment option. Here, a …

Recent advances in molecular, multimodal and theranostic ultrasound imaging

F Kiessling, S Fokong, J Bzyl, W Lederle… - Advanced drug delivery …, 2014 - Elsevier
Ultrasound (US) imaging is an exquisite tool for the non-invasive and real-time diagnosis of
many different diseases. In this context, US contrast agents can improve lesion delineation …

Ultrasound-mediated drug delivery to the brain: principles, progress and prospects

A Dasgupta, M Liu, T Ojha, G Storm, F Kiessling… - Drug Discovery Today …, 2016 - Elsevier
The blood–brain barrier (BBB) limits drug delivery to the central nervous system. When
combined with microbubbles, ultrasound can transiently permeate blood vessels in the …

Ultrasound‐mediated local drug and gene delivery using nanocarriers

QL Zhou, ZY Chen, YX Wang, F Yang… - BioMed research …, 2014 - Wiley Online Library
With the development of nanotechnology, nanocarriers have been increasingly used for
curative drug/gene delivery. Various nanocarriers are being introduced and assessed, such …

Mild hyperthermia with magnetic resonance-guided high-intensity focused ultrasound for applications in drug delivery

A Partanen, PS Yarmolenko, A Viitala… - International journal …, 2012 - Taylor & Francis
Purpose: Mild hyperthermia (40–45° C) is a proven adjuvant for radiotherapy and
chemotherapy. Magnetic resonance guided high intensity focused ultrasound (MR-HIFU) …

Focused ultrasound (FUS) for chronic pain management: approved and potential applications

L di Biase, E Falato, ML Caminiti… - Neurology Research …, 2021 - Wiley Online Library
Chronic pain is one of the leading causes of disability and disease burden worldwide,
accounting for a prevalence between 6.9% and 10% in the general population …

First clinical experience with a dedicated MRI-guided high-intensity focused ultrasound system for breast cancer ablation

LG Merckel, FM Knuttel, R Deckers, T van Dalen… - European …, 2016 - Springer
Objectives To assess the safety and feasibility of MRI-guided high-intensity focused
ultrasound (MR-HIFU) ablation in breast cancer patients using a dedicated breast platform …

Magnetic resonance guided high-intensity focused ultrasound for image-guided temperature-induced drug delivery

N Hijnen, S Langereis, H Grüll - Advanced drug delivery reviews, 2014 - Elsevier
Magnetic resonance guided high-intensity focused ultrasound (MR-HIFU) is a versatile
technology platform for noninvasive thermal therapies in oncology. Since MR-HIFU allows …

Reproductive impact of MRI-guided focused ultrasound surgery for fibroids: a systematic review of the evidence

NA Clark, SL Mumford, JH Segars - Current Opinion in Obstetrics …, 2014 - journals.lww.com
MRgFUS represents a minimally invasive treatment for uterine fibroids that is able to
improve the quality of life and fibroid size with durability. It is possible that MRgFUS could be …