The baroreceptor reflex is a relatively high gain control system that maintains arterial
pressure within normal limits. To a large extent, this is accomplished through central neural …

Renin angiotensin system (RAS) antagonists, angiotensin-converting enzyme (ACE)
inhibitors, and angiotensin II receptor antagonists are increasingly used to treat …

Angiotensin II receptor antagonists represent a new class of drugs that provide a sitespecific
blockade of the effects of angiotensin II. Losartan potassium, the first compound of this drug …

Discussion DR. RANDALL M. ZUSMAN (Director, Hypertension Division, Cardiac Unit,
Massachusetts General Hospital, and Assistant Professor of Medicine, Harvard Medical …

We studied the hemodynamic, neurohumoral, and biochemical effects of the novel
angiotensin type 1 (AT1) receptor antagonist irbesartan in 86 untreated patients with …

Congestive heart failure is characterized by a clear-cut impairment of arterial compliance of
medium-sized arteries, but whether this alteration is irreversible or can be favorably affected …

The baroreflex (BR) reflects autonomic blood pressure control. Alzheimer's disease (AD)
affects the autonomic system. Detailed properties of BR in AD are unknown. We …

Background Human studies have shown that the blood pressure lowering effects of
angiotensin converting enzyme inhibitors are accompanied by a reduction in plasma …

Previous studies have demonstrated that antihypertensive treatment resets baroreflex
control of heart rate (HR) and increases cardiac vagal baroreflex sensitivity. However, it is …

Calcium entry blockers are potent vasodilators and may be suitable for antihypertensive
therapy. We investigated hemodynamic responses together with changes of plasma …