[HTML][HTML] The role of adipokines in health and disease

VJ Clemente-Suárez, L Redondo-Flórez… - Biomedicines, 2023 - mdpi.com
Adipokines are cell-signaling proteins secreted by adipose tissue that has been related to a
low-grade state of inflammation and different pathologies. The present review aims to …

Obesity, oxidative stress, adipose tissue dysfunction, and the associated health risks: causes and therapeutic strategies

P Manna, SK Jain - Metabolic syndrome and related disorders, 2015 - liebertpub.com
Obesity is gaining acceptance as a serious primary health burden that impairs the quality of
life because of its associated complications, including diabetes, cardiovascular diseases …

[HTML][HTML] The association between psoriasis and obesity: a systematic review and meta-analysis of observational studies

AW Armstrong, CT Harskamp, EJ Armstrong - Nutrition & diabetes, 2012 - nature.com
Objective: Psoriasis is an inflammatory skin disease affecting 2–4% of the world population.
The objective of this study was to perform a systematic review and meta-analysis …

Adipokine dysregulation, adipose tissue inflammation and metabolic syndrome

E Maury, SM Brichard - Molecular and cellular endocrinology, 2010 - Elsevier
Obesity plays a causative role in the pathogenesis of the metabolic syndrome. Adipokines
may link obesity to its co-morbidities. Most adipokines with pro-inflammatory properties are …

The pathogenetic role of cortisol in the metabolic syndrome: a hypothesis

P Anagnostis, VG Athyros, K Tziomalos… - The Journal of …, 2009 - academic.oup.com
Context: The metabolic syndrome (MetS) is a cluster of metabolic abnormalities that
increase the risk for type 2 diabetes mellitus and vascular disease. The common …

Adipokines: a link between obesity and dementia?

AJ Kiliaan, IAC Arnoldussen, DR Gustafson - The Lancet Neurology, 2014 - thelancet.com
Being overweight or obese, as measured with body-mass index or central adiposity (waist
circumference), and the trajectory of body-mass index over the life course have been …

Mitochondrial dysfunction in NASH: causes, consequences and possible means to prevent it

K Begriche, A Igoudjil, D Pessayre, B Fromenty - Mitochondrion, 2006 - Elsevier
Calorie-enriched diet and lack of exercise are causing a worldwide surge of obesity, insulin
resistance and lipid accretion in liver (ie hepatic steatosis), which can lead to steatohepatitis …

Maternal tract factors contribute to paternal seminal fluid impact on metabolic phenotype in offspring

JJ Bromfield, JE Schjenken, PY Chin… - Proceedings of the …, 2014 - National Acad Sciences
Paternal characteristics and exposures influence physiology and disease risks in progeny,
but the mechanisms are mostly unknown. Seminal fluid, which affects female reproductive …

Ceramides in insulin resistance and lipotoxicity

SA Summers - Progress in lipid research, 2006 - Elsevier
Obesity predisposes individuals to the development of insulin resistance in skeletal muscle
and the liver, and researchers have recently proposed two mechanisms by which excess …

Physical activity and modulation of systemic low-level inflammation

H Bruunsgaard - Journal of leukocyte biology, 2005 - academic.oup.com
It has been recognized for some time that cardiovascular disease and type 2 diabetes are, to
a major extent, inflammatory disorders associated with an environment characterized by a …