Frontotemporal dementia (FTD) is a neurodegenerative disease of growing interest, since it
accounts for up to 10% of middle-age-onset dementias and entails a social, economic, and …

Parkinson's disease (PD) is a debilitating neurological disorder characterized by the
impairment of the motor system, resulting in symptoms such as resting tremor, cogwheel …

Neurodegenerative disorders are characterised by progressive neuron loss in specific brain
areas. The most common are Alzheimer's disease and Parkinson's disease; in both cases …

Background The cerebrospinal fluid (CSF), which surrounds the brain and spinal cord, is
predominantly produced by the choroid plexus of the ventricle. Although CSF-derived …

Exosomes are extracellular vesicles with diameters of about 100 nm that are naturally
secreted by cells into body fluids. They are derived from endosomes and are wrapped in …

With the increasing number of patients suffering from central nervous system (CNS)
diseases, there is a pressing demand to acquire dependable diagnostic tools in the early …

Alzheimer's disease (AD) is a progressive neurodegenerative disorder and represents the
leading cause of cognitive impairment and dementia in older individuals throughout the …

Neurodegenerative diseases (NDs) such as Alzheimer's Disease (AD) and Parkinson's
Disease (PD) are devastating conditions that can develop without noticeable symptoms …

Background Pathological cerebral conditions may manifest in altered composition of the
cerebrospinal fluid (CSF). Although diagnostic CSF analysis seeks to establish pathological …

Proteinopathies are a large group of neurodegenerative diseases caused by both genetic
and sporadic mutations in particular genes which can lead to alterations of the protein …