Cardiovascular diseases (CVDs) are the main cause of death among patients with type 2
diabetes mellitus (T2DM), particularly in low-and middle-income countries. To effectively …

Arterial hypertension is a leading cause of death globally. Due to ageing, the rising
incidence of obesity, and socioeconomic and environmental changes, its incidence …

Prediabetes affects at least 1 in 3 adults in the US and one-fifth in Europe. Although
guidelines advocate aggressive management of lipid parameters in diabetes, most …

Background Controversy exists as to whether the threshold for blood pressure-lowering
treatment should differ between people with and without type 2 diabetes. We aimed to …

• The specific situation of the patient. Unless otherwise provided for by national regulations,
off-label use of medication should be limited to situations where it is in the patient's interest …

Abstract Purpose of Review To review the recent large-scale randomised evidence on
pharmacologic reduction in blood pressure for the primary and secondary prevention of …

Background Metformin shows beneficial effects on cardiometabolic health in diabetic
individuals. However, the beneficial effects in the general population, especially in non …

Diabetes Mellitus (DM) is amongst the most notable causes of years of life lost worldwide
and its prevalence increases perpetually. The disease is characterized as multisystemic …

Background Beta-blocker (BB) and calcium channel blocker (CCB) antihypertensive drugs
are commonly used in pregnancy. However, data on their relative impact on maternal and …

Insulin resistance is a major contributor to the pathogenesis of several human diseases,
including type 2 diabetes, hypertension, and hyperlipidemia. Notably, insulin resistance and …