Background: The catalytic subunit of telomerase, telomerase reverse transcriptase (TERT),
has protective functions in the cardiovascular system. TERT is not only present in the …

Major advances in biomedical imaging have occurred over the last 2 decades and now
allow many physiological, cellular, and molecular processes to be imaged noninvasively in …

Despite the clear association between myocardial injury, heart failure and depressed
myocardial energetics, little is known about upstream signals responsible for remodeling …

Background: Heart failure is a leading cause of death worldwide and is associated with the
rising prevalence of obesity, hypertension, and diabetes. O-GlcNAcylation (the attachment of …

Cardioprotection by salvage of the infarct-affected myocardium is an unmet yet highly
desired therapeutic goal. To develop new dedicated therapies, experimental myocardial …

Aims Non-compaction cardiomyopathy is a devastating genetic disease caused by
insufficient consolidation of ventricular wall muscle that can result in inadequate cardiac …

Acute myocardial infarction (MI) induces an extensive sterile inflammation, which is
dominated in the early phase by invading neutrophils and monocytes/macrophages. The …

The aim of this study was to assess the accuracy of an algorithm for automated
measurement of left ventricular ejection fraction (LVEF) available on handheld ultrasound …

The pathological role of adipose derived fatty acids following myocardial infarction has long
been hypothesized. However, most methods for reducing adipocyte lipolysis have significant …

Insulin-like growth factor 1 (IGF1) is an anabolic hormone that controls the growth and
metabolism of many cell types. However, IGF1 also mediates cardio-protective effects after …