Cannabidiol (CBD) is a non-psychotropic phytocannabinoid of the plant Cannabis sativa L.
CBD is increasingly being explored as an alternative to conventional therapies to treat …

Cannabis is well established to impact affective states, emotion and perceptual processing,
primarily through its interactions with the endocannabinoid system. While cannabis use is …

The endocannabinoid signaling system (ECSS) is altered by exposure to stress and
mediates and modulates the effects of stress on the brain. Considerable preclinical data …

The cannabis plant has been used for centuries to manage the symptoms of various
ailments including pain. Hundreds of chemical compounds have been identified and …

Acute pharmacological inhibition of the anandamide-degrading enzyme, fatty acid amide
hydrolase (FAAH), prolongs the regulatory effects of endocannabinoids and reverses the …

Anxiety-and trauma-related disorders are severe illnesses with high prevalence. Current
treatment options leave room for improvement and the endocannabinoid system (ECS) has …

Cannabis use induces a plethora of actions on the CNS via its active chemical ingredients,
the so-called phytocannabinoids. These compounds have been frequently associated with …

Social anxiety disorder (SAD) is a debilitating disorder, characterized by fear and anxiety in
social situations. Evidence suggests that the levels of SAD are rising, in particularly after the …

Background Cannabis use is more common among adults with anxiety. Cannabis
legalization is occurring rapidly across the United States (US) and individuals may use …

Chronic pain is a major public health issue that frequently leads to analgesic opioid
prescriptions. These prescriptions could cause addiction issues in high-risk patients with …