Microorganisms in the environment can often adapt to use xenobiotic chemicals as novel
growth and energy substrates. Specialized enzyme systems and metabolic pathways for the …

▪ Abstract The xyl genes of Pseudomonas putida TOL plasmid that specify catabolism of
toluene and xylenes are organized in four transcriptional units: the upper-operon …

We have constructed a series of derivatives of the Ω interposon [Prentki and Krisch, Gene 29
(1984) 303–313] that can be used for in vitro insertional mutagenesis. Each of these DNA …

The TOL plasmid upper pathway operon encodes enzymes involved in the catabolism of
aromatic hydrocarbons such as toluene and xylenes. The regulator of the gene pathway, the …

Publisher Summary The chapter introduces TOL plasmids and discusses pathways for
toluene and xylenes catabolisms, regulation of catabolic genes, and evolution of catabolic …

Aromatic hydrocarbons are ubiquitous in the environment. They are produced primarily by
the pyrolysis of organic material.'The mutagenic and carcinogenic nature of several aromatic …

The meta-cleavage pathway for catechol is one of the major routes for the microbial
degradation of aromatic compounds. Pseudomonas sp. strain CF600 grows efficiently on …

At present, the best-understood catabolic plasmid is the TOL plasmid, which encodes the
enzymes that degrade toluene. The archetype TOL plasmid, pWW0, was first described in …

TOL plasmid pWWO of Pseudomonas putida contains two operons that specify a pathway
for the degradation of aromatic hydrocarbons. The upper pathway operon encodes the …

The xylH gene encoding 4-oxalocrotonate tautomerase (4-OT) has been located on a
subclone of the Pseudomonas putida mt-2 TOL plasmid pWW0 and inserted into an …