[HTML][HTML] Proteomic Discovery of RNA-Protein Molecular Clamps Using a Thermal Shift Assay with ATP and RNA (TSAR)

SI Goldstein, AC Fan, Z Wang, SK Naineni, J Lengqvist… - bioRxiv, 2024 - ncbi.nlm.nih.gov
Uncompetitive inhibition is an effective strategy for suppressing dysregulated enzymes and
their substrates, but discovery of suitable ligands depends on often-unavailable structural …

The DEAD-box protein p68 and β-catenin: the crucial regulators of FOXM1 gene expression in arbitrating colorectal cancer

S Tabassum, M Basu, MK Ghosh - bioRxiv, 2022 - biorxiv.org
Abstract Forkhead box M1 (FOXM1), a vital member of the Forkhead box family of
transcription factors, helps in mediating oncogenesis. However, limited knowledge exists …

Single-cell Rapid Capture Hybridization sequencing (scRaCH-seq) to reliably detect isoform usage and coding mutations in targeted genes at a single-cell level

H Peng, JS Jabbari, L Tian, CC Chua, NS Anstee… - bioRxiv, 2024 - biorxiv.org
Single-cell long-read sequencing has transformed our understanding of isoform usage and
the mutation heterogeneity between cells. Despite unbiased in-depth analysis, the low …

The MYCN oncoprotein and helicases DDX17 and DDX5 have opposite effects on the production of chimeric transcripts in neuroblastoma cells

V Clerc, J Valat, X Grand, N Fontrodona, M Bazire… - bioRxiv, 2024 - biorxiv.org
DEAD box helicases DDX17 and DDX5 control the termination of transcription and the
associated cleavage of the 3'end of transcripts. Here we show that the transcriptional …

DDX5 和DDX17 在卵巢癌组织中的表达及对人卵巢癌细胞系SKOV3 增殖和耐药的影响

黄洁, 李润博, 郭建新, 韩健 - 基础医学与临床, 2023 - journal11.magtechjournal.com
目的分析DDX5 和DDX17 在卵巢癌中的表达水平及与患者生存期的关系, 并研究其对人卵巢癌
细胞系SKOV3 增殖及耐药的影响. 方法选取40 例卵巢癌和27 例正常卵巢上皮标本, 采用RT …

[PDF][PDF] Research progress of DEAD-box polypeptide 5 in breast cancer

M GE, Z HE, L YANG, C LIU, J CHEN… - Chin J Clin Res, 2024 - zglcyj.cnjournals.com
Corresponding author: WANG Kuanyu, E-mail: wangkuanyu_1964@ 163. com Abstract:
Breast cancer, as a malignant tumor threatening the survival of women in China, its …

Rôle des hélicases DDX5 et DDX17 dans l'expression et la maturation des ARN pré-messagers dans le contexte de pathologies neuro-développementales

V Clerc - 2023 - theses.hal.science
L'étape de maturation de l'extrémité 3'des ARNm est cruciale à la fois pour assurer leur
libération de la chromatine et exportation au cytoplasme, mais permet aussi la production …

Expression of DDX5 and DDX17 in ovarian cancer tissues and their effects on proliferation and drug resistance of human ovarian cancer cell line SKOV3

J HUANG, R LI, J GUO, J HAN - Basic & Clinical …, 2023 - journal11.magtechjournal.com
Objective To analyze the expression of DDX5 and DDX17 in ovarian cancer and their
relationship with patient survival, and to study the effects of DDX5 and DDX17 on …