Neutrophils are the most abundant circulating leukocytes, being the first line of defence
against bacterial and fungal infections. However, neutrophils also contribute to tissue …

Traditionally, neutrophils have been acknowledged to be the first immune cells that are
recruited to an inflamed tissue and have mainly been considered in the context of acute …

Neutrophils promptly accumulate in large numbers at sites of tissue injury. Injuries to the skin
or mucosae disrupt barriers against the external environment, and the bactericidal actions of …

There are well-established links between acute inflammation and successful tissue repair
across evolution. Innate immune reactions contribute significantly to pathogen clearance …

In their classic 1976 paper, Page & Schroeder described the histopathologic events and the
types of myeloid cells and lymphocytes involved in the initiation and progression of …

Aging is a complex phenomenon leading to numerous changes in the physiological systems
of the body. One of the most important changes, called immunosenescence, occurs in the …

Neutrophils are the most abundant human white blood cell and constitute a first line of
defense in the innate immune response. Neutrophils are short-lived cells and thus the …

The increased prevalence and severity of periodontal disease have long been associated
with aging, such that this oral condition affects the majority of the adult population over 50 …

Neutrophils have been historically associated with antimicrobial functions in acute infections
but are now appreciated as functionally versatile cells with critical roles in chronic …

Aging of the immune system in humans and animals is characterized by a decline in both
adaptive and innate immune responses. Paradoxically, aging is also associated with a state …