[HTML][HTML] Microglia in neurodegenerative diseases: mechanism and potential therapeutic targets
C Gao, J Jiang, Y Tan, S Chen - Signal transduction and targeted …, 2023 - nature.com
Microglia activation is observed in various neurodegenerative diseases. Recent advances in
single-cell technologies have revealed that these reactive microglia were with high spatial …
single-cell technologies have revealed that these reactive microglia were with high spatial …
[HTML][HTML] Microglia in neurological diseases: a road map to brain-disease dependent-inflammatory response
S Bachiller, I Jiménez-Ferrer, A Paulus… - Frontiers in cellular …, 2018 - frontiersin.org
Microglia represent a specialized population of macrophages-like cells in the central
nervous system (CNS) considered immune sentinels that are capable of orchestrating a …
nervous system (CNS) considered immune sentinels that are capable of orchestrating a …
The role of oxidative stress in Parkinson's disease
V Dias, E Junn, MM Mouradian - Journal of Parkinson's …, 2013 - content.iospress.com
Oxidative stress plays an important role in the degeneration of dopaminergic neurons in
Parkinson's disease (PD). Disruptions in the physiologic maintenance of the redox potential …
Parkinson's disease (PD). Disruptions in the physiologic maintenance of the redox potential …
Microglia in Parkinson's disease
MS Ho - Neuroglia in neurodegenerative diseases, 2019 - Springer
Microglia are the most abundant immune cells in the central nervous system (CNS), where
they interact with neurons and exhibit a wide array of functions in physiological and …
they interact with neurons and exhibit a wide array of functions in physiological and …
[HTML][HTML] Parkinson's disease: animal models and dopaminergic cell vulnerability
J Blesa, S Przedborski - Frontiers in neuroanatomy, 2014 - frontiersin.org
Parkinson's disease (PD) is a neurodegenerative disorder that affects about 1.5% of the
global population over 65 years of age. A hallmark feature of PD is the degeneration of the …
global population over 65 years of age. A hallmark feature of PD is the degeneration of the …
[HTML][HTML] Targeting microglial activation states as a therapeutic avenue in Parkinson's disease
SR Subramaniam, HJ Federoff - Frontiers in aging neuroscience, 2017 - frontiersin.org
Parkinson's disease (PD) is a chronic and progressive disorder characterized
neuropathologically by loss of dopamine neurons in the substantia nigra, intracellular …
neuropathologically by loss of dopamine neurons in the substantia nigra, intracellular …
Ferroptosis and cell death mechanisms in Parkinson's disease
Symptoms of Parkinson's disease arise due to neuronal loss in multiple brain regions,
especially dopaminergic neurons in the substantia nigra pars compacta. Current therapies …
especially dopaminergic neurons in the substantia nigra pars compacta. Current therapies …
[HTML][HTML] Neuroinflammation and Parkinson's disease—From neurodegeneration to therapeutic opportunities
B Araújo, R Caridade-Silva, C Soares-Guedes… - Cells, 2022 - mdpi.com
Parkinson's disease (PD) is the second most prevalent neurodegenerative disorder
worldwide. Clinically, it is characterized by a progressive degeneration of dopaminergic …
worldwide. Clinically, it is characterized by a progressive degeneration of dopaminergic …
[HTML][HTML] Triggering of inflammasome by aggregated α–synuclein, an inflammatory response in synucleinopathies
Parkinson's disease (PD) is one of the most common neurodegenerative diseases. It is
characterized by the loss of dopaminergic neurons in the substantia nigra pars compacta of …
characterized by the loss of dopaminergic neurons in the substantia nigra pars compacta of …
[HTML][HTML] Microglia response during Parkinson's disease: alpha-synuclein intervention
SA Ferreira, M Romero-Ramos - Frontiers in cellular neuroscience, 2018 - frontiersin.org
The discovery of the central role played by the protein alpha-synuclein in Parkinson's
disease and other Lewy body brain disorders has had a great relevance in the …
disease and other Lewy body brain disorders has had a great relevance in the …