The prevention, diagnosis, and management of infectious disease in transplantation are
major contributors to improved outcomes in organ transplantation. The risk of serious …

The ability to successfully transplant solid organs and hematopoietic stem cells represents
one of the landmark medical achievements of the twentieth century. Solid organ …

Though an important cause of morbidity and mortality in solid organ transplantation (SOT),
the long-term outcomes of cytomegalovirus (CMV) disease treatment have not been well …

Preemptive antiviral therapy in transplant patients is thought to be less likely to lead to
antiviral resistance than is routine prophylaxis. Cytomegalovirus (CMV)–seropositive lung …

Abstract Ganciclovir-resistant (GanR) cytomegalovirus (CMV) is an emerging clinical
problem in organ transplant recipients, particularly recipients of kidney and pancreas and …

Ganciclovir is a nucleoside guanosine analogue which incorporates ganciclovir
triphosphate (the active moiety) into DNA during elongation, thereby inhibiting viral …

Cytomegalovirus (CMV) infection remains a serious problem in lung transplant recipients.
Development of potent oral antiviral agents, molecular techniques for the detection of …

Hintergrund Die Colitis ulcerosa (CU) ist neben dem Morbus Crohn die wichtigste chronisch-
entzündliche Darmerkrankung (CED). Die Inzidenz für die Colitis ulcerosa liegt in …

Whether preemptive therapy or universal prophylaxis with ganciclovir is the optimal
approach against cytomegalovirus (CMV) remains unresolved. Controversy abounds with …

The introduction and combination of more-potent immunosuppressive regimens, and the
increased transplantation of organs into more severely ill patients, have again placed …