Many new insights into the diagnosis, pathogenesis, clinical manifestation, treatment and
prognosis of patients with AML reflect the heterogeneity of the disease. The initial …

Children with Down syndrome (DS) are at an increased risk of developing transient
abnormal myelopoiesis (TAM) and acute leukemia. Aberrant expression of CD56 has been …

Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a rare and aggressive myeloid
malignancy which characteristically expresses an atypical phenotype including CD123+ …

Background: After long-term analysis of the JALSG-APL204 study we recently reported that
maintenance therapy with tamibarotene was more effective than all-trans retinoic acid …

We describe algorithms for discovering immunophenotypes from large collections of flow
cytometry samples and using them to organize the samples into a hierarchy based on …

Leukemia cell lines have been widely used in the hematology field to unravel mechanistic
insights and to test new therapeutic strategies. Myelodysplastic syndromes (MDS) comprise …

Flow cytometry‐based immunophenotyping is a mainstay of diagnostics in acute myeloid
leukaemia (AML). Aberrant CD56 and T‐cell antigen expression is observed in a fraction …

Abstract Typical BCR:: ABL1-negative myeloproliferative neoplasms (MPN) are mainly
referred to as polycythemia vera (PV), essential thrombocythemia (ET), and primary …

Natural killer cells mediate antibody‐dependent cell‐mediated cytotoxicity, and CD16 exerts
key functions to induce antibody‐dependent cell‐mediated cytotoxicity response. Because …

Selection of resistant clones following intensive chemotherapy is a common obstacle for
cure in many cancers, particularly in acute myeloid leukemia (AML). In AML, clone-specific …