[HTML][HTML] Tetraspanins: host factors in viral infections

CS New, ZY Lee, KS Tan, AHP Wong… - International Journal of …, 2021 - mdpi.com
Tetraspanins are transmembrane glycoproteins that have been shown increasing interest as
host factors in infectious diseases. In particular, they were implicated in the pathogenesis of …

Multiomics integration-based molecular characterizations of COVID-19

CX Li, J Gao, Z Zhang, L Chen, X Li… - Briefings in …, 2022 - academic.oup.com
Abstract The coronavirus disease 2019 (COVID-19) pandemic, caused by the severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2), rapidly became a global health …

[HTML][HTML] Differential co-expression network analysis reveals key hub-high traffic genes as potential therapeutic targets for COVID-19 pandemic

A Hasankhani, A Bahrami, N Sheybani, B Aria… - Frontiers in …, 2021 - frontiersin.org
Background The recent emergence of COVID-19, rapid worldwide spread, and incomplete
knowledge of molecular mechanisms underlying SARS-CoV-2 infection have limited …

[HTML][HTML] Genome-wide CRISPR screens identify GATA6 as a proviral host factor for SARS-CoV-2 via modulation of ACE2

M Israeli, Y Finkel, Y Yahalom-Ronen, N Paran… - Nature …, 2022 - nature.com
The global spread of SARS-CoV-2 led to major economic and health challenges worldwide.
Revealing host genes essential for infection by multiple variants of SARS-CoV-2 can provide …

[HTML][HTML] Acute SARS-CoV-2 infection is associated with an increased abundance of bacterial pathogens, including Pseudomonas aeruginosa in the nose

NS Rhoades, AN Pinski, AN Monsibais, A Jankeel… - Cell Reports, 2021 - cell.com
Research conducted on severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
pathogenesis and coronavirus disease 2019 (COVID-19) generally focuses on the systemic …

Systems-level profiling of early peripheral host-response landscape variations across COVID-19 severity states in an Indian cohort

U Banerjee, S Chunchanur, KN Balaji, A Singh… - Genes & …, 2023 - nature.com
Host immune response to COVID-19 plays a significant role in regulating disease severity.
Although big data analysis has provided significant insights into the host biology of COVID …

[HTML][HTML] Identification of COVID-19-specific immune markers using a machine learning method

H Li, F Huang, H Liao, Z Li, K Feng… - Frontiers in Molecular …, 2022 - frontiersin.org
Notably, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has a tight
relationship with the immune system. Human resistance to COVID-19 infection comprises …

Updated pharmacological effects of Lonicerae japonicae flos, with a focus on its potential efficacy on coronavirus disease–2019 (COVID-19)

H Zhao, S Zeng, L Chen, Q Sun, M Liu, H Yang… - Current Opinion in …, 2021 - Elsevier
Lonicerae japonicae flos (LJF), known as Jin Yin Hua in Chinese, is one of the most
commonly used traditional Chinese herbs and nutraceuticals. Nowadays, LJF is broadly …

Selection of ideal reference genes for gene expression analysis in COVID-19 and mucormycosis

S Kumar, A Ahmad, N Kushwaha… - Microbiology …, 2022 - Am Soc Microbiol
Selection of reference genes during real-time quantitative PCR (qRT-PCR) is critical to
determine accurate and reliable mRNA expression. Nonetheless, not a single study has …

SARS-CoV-2 infection severity and mortality is modulated by repeat-mediated regulation of alternative splicing

P Mehta, P Chattopadhyay, V Ravi, B Tarai… - Microbiology …, 2023 - Am Soc Microbiol
Like single-stranded RNA viruses, SARS-CoV-2 hijacks the host transcriptional machinery
for its own replication. Numerous traditional differential gene expression-based …