RNA packaging into extracellular vesicles: An orchestra of RNA‐binding proteins?
Extracellular vesicles (EVs) are heterogeneous membranous particles released from the
cells through different biogenetic and secretory mechanisms. We now conceive EVs as …
cells through different biogenetic and secretory mechanisms. We now conceive EVs as …
Y-box-binding protein 1 (YB-1) and its functions
IA Eliseeva, ER Kim, SG Guryanov… - Biochemistry …, 2011 - Springer
This review describes the structure and functions of Y-box binding protein 1 (YB-1) and its
homologs. Interactions of YB-1 with DNA, mRNAs, and proteins are considered. Data on the …
homologs. Interactions of YB-1 with DNA, mRNAs, and proteins are considered. Data on the …
Obstacles and opportunities in the functional analysis of extracellular vesicle RNA–an ISEV position paper
The release of RNA-containing extracellular vesicles (EV) into the extracellular milieu has
been demonstrated in a multitude of different in vitro cell systems and in a variety of body …
been demonstrated in a multitude of different in vitro cell systems and in a variety of body …
Y-box protein 1 is required to sort microRNAs into exosomes in cells and in a cell-free reaction
MJ Shurtleff, MM Temoche-Diaz, KV Karfilis, S Ri… - elife, 2016 - elifesciences.org
Exosomes are small vesicles that are secreted from metazoan cells and may convey
selected membrane proteins and small RNAs to target cells for the control of cell migration …
selected membrane proteins and small RNAs to target cells for the control of cell migration …
Selective export into extracellular vesicles and function of tRNA fragments during T cell activation
NT Chiou, R Kageyama, KM Ansel - Cell reports, 2018 - cell.com
The discovery of microRNA (miRNA) sorting into extracellular vesicles (EVs) revealed a
novel mode of intercellular communication and uncovered a link between cellular …
novel mode of intercellular communication and uncovered a link between cellular …
Unraveling tumor–immune heterogeneity in advanced ovarian cancer uncovers immunogenic effect of chemotherapy
A Jiménez-Sánchez, P Cybulska, KLV Mager… - Nature Genetics, 2020 - nature.com
In metastatic cancer, the degree of heterogeneity of the tumor microenvironment (TME) and
its molecular underpinnings remain largely unstudied. To characterize the tumor–immune …
its molecular underpinnings remain largely unstudied. To characterize the tumor–immune …
Canonical and non-canonical Notch ligands
B D'Souza, L Meloty-Kapella, G Weinmaster - Current topics in …, 2010 - Elsevier
Notch signaling induced by canonical Notch ligands is critical for normal embryonic
development and tissue homeostasis through the regulation of a variety of cell fate decisions …
development and tissue homeostasis through the regulation of a variety of cell fate decisions …
Cold shock proteins: from cellular mechanisms to pathophysiology and disease
JA Lindquist, PR Mertens - Cell Communication and Signaling, 2018 - Springer
Cold shock proteins are multifunctional RNA/DNA binding proteins, characterized by the
presence of one or more cold shock domains. In humans, the best characterized members of …
presence of one or more cold shock domains. In humans, the best characterized members of …
A comprehensive review of the functions of YB-1 in cancer stemness, metastasis and drug resistance
The Y Box binding protein 1 (YB-1) is a member of the highly conserved Cold Shock Domain
protein family with multifunctional properties both in the cytoplasm and inside the nucleus …
protein family with multifunctional properties both in the cytoplasm and inside the nucleus …
Y-box binding proteins in mRNP assembly, translation, and stability control
D Mordovkina, DN Lyabin, EA Smolin, EM Sogorina… - Biomolecules, 2020 - mdpi.com
Y-box binding proteins (YB proteins) are DNA/RNA-binding proteins belonging to a large
family of proteins with the cold shock domain. Functionally, these proteins are known to be …
family of proteins with the cold shock domain. Functionally, these proteins are known to be …