Pseudomonas aeruginosa: An Audacious Pathogen with an Adaptable Arsenal of Virulence Factors

I Jurado-Martín, M Sainz-Mejías… - International journal of …, 2021 - mdpi.com
Pseudomonas aeruginosa is a dominant pathogen in people with cystic fibrosis (CF)
contributing to morbidity and mortality. Its tremendous ability to adapt greatly facilitates its …

Pseudomonas aeruginosa: Recent Advances in Vaccine Development

M Killough, AM Rodgers, RJ Ingram - Vaccines, 2022 - mdpi.com
Pseudomonas aeruginosa is an important opportunistic human pathogen. Using its arsenal
of virulence factors and its intrinsic ability to adapt to new environments, P. aeruginosa …

Strong immune responses and protection of PcrV and OprF-I mRNA vaccine candidates against Pseudomonas aeruginosa

X Wang, C Liu, N Rcheulishvili, D Papukashvili, F Xie… - npj Vaccines, 2023 - nature.com
Pseudomonas aeruginosa (PA) is a leading cause of hospital-acquired and ventilator-
associated pneumonia. The multidrug-resistance (MDR) rate of PA is increasing making the …

Pseudomonas aeruginosa virulence attenuation by inhibiting siderophore functions

GJ Jeong, F Khan, S Khan, N Tabassum… - Applied Microbiology …, 2023 - Springer
Pseudmonas aeruginosa is a Gram-negative bacterium known to be ubiquitous and
recognized as one of the leading causes of infections such as respiratory, urinary tract …

[HTML][HTML] What Is New in the Anti–Pseudomonas aeruginosa Clinical Development Pipeline Since the 2017 WHO Alert?

S Reig, A Le Gouellec, S Bleves - Frontiers in Cellular and Infection …, 2022 - frontiersin.org
The spread of antibiotic-resistant bacteria poses a substantial threat to morbidity and
mortality worldwide. Carbapenem-resistant Pseudomonas aeruginosa (CRPA) are …

IgY antibodies: The promising potential to overcome antibiotic resistance

SA El-Kafrawy, AT Abbas, C Oelkrug… - Frontiers in …, 2023 - frontiersin.org
Antibiotic resistant bacteria are a growing threat to global health security. Whilst the
emergence of antimicrobial resistance (AMR) is a natural phenomenon, it is also driven by …

Immunization with lytic polysaccharide monooxygenase CbpD induces protective immunity against Pseudomonas aeruginosa pneumonia

F Askarian, CM Tsai, G Cordara… - Proceedings of the …, 2023 - National Acad Sciences
Pseudomonas aeruginosa (PA) CbpD belongs to the lytic polysaccharide monooxygenases
(LPMOs), a family of enzymes that cleave chitin or related polysaccharides. Here, we …

Concordance in pathogen identification at the upper and lower respiratory tract of children with severe pneumonia

H Wang, X Li, Y Zheng, LM Verhagen, J Gu, L Li… - BMC infectious …, 2023 - Springer
Background Nasopharyngeal swabs are taken to determine the causative agent of
community acquired pneumonia (CAP), while the reliability of upper respiratory tract …

Assessment of listing and categorisation of animal diseases within the framework of the Animal Health Law (Regulation (EU) No 2016/429): infection with Equine …

EFSA Panel on Animal Health and Welfare … - EFSA …, 2022 - Wiley Online Library
Equine Herpesvirus‐1 infection has been assessed according to the criteria of the Animal
Health Law (AHL), in particular criteria of: Article 7 on disease profile and impacts, Article 5 …

[HTML][HTML] Virulence mechanisms of Mycobacterium abscessus: Current knowledge and implications for vaccine design

KC Ferrell, MD Johansen, JA Triccas… - Frontiers in …, 2022 - frontiersin.org
Mycobacterium abscessus is a member of the non-tuberculous mycobacteria (NTM) group,
responsible for chronic infections in individuals with cystic fibrosis (CF) or those otherwise …