Association of Wiskott-Aldrich syndrome protein (WASp) in epigenetic regulation of B cell differentiation in non-small-cell lung cancer (NSCLC)

N Chandnani, A Mandal, I Gupta, O Mukherjee… - Medical Oncology, 2023 - Springer
Non-small-cell lung cancer (NSCLC) accounts for approximately 85% of all lung cancer
which is the deadliest type of cancer for both men and women. Previous studies already …

Emerging role of long non-coding RNAs in normal and malignant hematopoiesis

FY Wang, ZY Gu, CJ Gao - Chinese Medical Journal, 2020 - mednexus.org
Long noncoding RNAs (lncRNAs) have recently been discovered and are increasingly
recognized as vital components of modern molecular biology. Accumulating evidence …

[PDF][PDF] miRNA-125 家族与自身免疫性疾病关系的研究进展

武志慧, 孙晓林, 王慧 - 中国比较医学杂志, 2022 - zgbjyx.cnjournals.com
MicroRNAs (miRNAs) 是一类内源性非编码小分子RNA, 长度为20~ 23 个核苷酸. MicroRNA-
125 (miR-125) 是一个高度保守的miRNA 家族, 由miR-125a, miR-125b-1 和miR-125b-2 组成 …

Distinct requirements of CHD4 during B cell development and antibody response

WF Yen, R Sharma, M Cols, CM Lau, A Chaudhry… - Cell reports, 2019 - cell.com
The immunoglobulin heavy chain (Igh) locus features a dynamic chromatin landscape to
promote class switch recombination (CSR), yet the mechanisms that regulate this landscape …

A Posttranscriptional Pathway of CD40 Ligand mRNA Stability Is Required for the Development of an Optimal Humoral Immune Response

B Narayanan, D Prado de Maio, J La Porta… - The Journal of …, 2021 - journals.aai.org
Abstract CD40 ligand (CD40L) mRNA stability is dependent on an activation-induced
pathway that is mediated by the binding complexes containing the multifunctional RNA …

Therapy of infectious diseases using epigenetic approaches

Z Zhou, S Rajasingh, B Barani, S Samanta… - Epigenetics in Human …, 2018 - Elsevier
Epigenetic modifications are the heritable changes in gene expression patterns that are
independent of primary DNA sequence changes and affect the outcome of a locus or …

Integrative analysis of long noncoding RNAs in patients with graft-versus-host disease

F Wang, L Luo, Z Gu, N Yang, L Wang, C Gao - Acta Haematologica, 2020 - karger.com
Background: Chronic graft-versus-host disease (cGVHD) remains a major cause of late non-
recurrence mortality despite remarkable improvements in the field of allogeneic …

Survey of activation‐induced genome architecture reveals a novel enhancer of Myc

WF Chan, HD Coughlan, M Ruhle… - … and Cell Biology, 2023 - Wiley Online Library
The transcription factor Myc is critically important in driving cell proliferation, a function that is
frequently dysregulated in cancer. To avoid this dysregulation Myc is tightly controlled by …

Interferon-gamma DNA methylation is affected by mycophenolic acid but not by tacrolimus after T-cell activation

FS Peters, AMA Peeters, LJ Hofland… - Frontiers in …, 2017 - frontiersin.org
Immunosuppressive drug therapy is required to treat patients with autoimmune disease and
patients who have undergone organ transplantation. The main targets of the …

Therapy of infectious diseases using epigenetic approaches

SG Perales, S Rajasingh, Z Zhou… - Epigenetics in Human …, 2024 - Elsevier
Epigenetic modifications are the heritable changes in gene expression patterns that are
independent of primary DNA sequence changes and affect the expression of a locus or …