Clinical relevance of domain-specific phospholipase A2 receptor 1 antibody levels in patients with membranous nephropathy

L Reinhard, G Zahner, S Menzel… - Journal of the …, 2020 - journals.lww.com
Background Antibodies against phospholipase A 2 receptor 1 (PLA 2 R1) are found in 80%
of patients with membranous nephropathy, and previous studies described three …

Anti-PLA2R antibodies as a prognostic factor in PLA2R-related membranous nephropathy

SA Timmermans, MA Abdul Hamid… - American journal of …, 2015 - karger.com
Background: The natural course of idiopathic membranous nephropathy (MN) varies, as it is
known through favorable outcomes in most patients. However, one third of patients with …

The Role of PLA2R in Primary Membranous Nephropathy: Do We Still Need a Kidney Biopsy?

T McDonnell, HHL Wu, S Sinha, R Chinnadurai - Genes, 2023 - mdpi.com
Membranous nephropathy (MN) is the most prevalent cause of nephrotic syndrome amongst
the non-diabetic adult population. A fifth of idiopathic nephrotic syndrome cases can be …

Membranous nephropathy and anti‐podocytes antibodies: implications for the diagnostic workup and disease management

A Pozdzik, I Brochériou, C David… - BioMed research …, 2018 - Wiley Online Library
The discovery of circulating antibodies specific for native podocyte antigens has transformed
the diagnostic workup and greatly improved management of idiopathic membranous …

Multi-antibody composition in lupus nephritis: isotype and antigen specificity make the difference

A Bonanni, A Vaglio, M Bruschi, RA Sinico… - Autoimmunity …, 2015 - Elsevier
Research on autoimmune processes involved in glomerulonephritis has been for years
based on experimental models. Recent progress in proteomics has radically modified …

Pre‐transplant phospholipase A2 receptor autoantibody concentration is associated with clinically significant recurrence of membranous nephropathy post‐kidney …

G Gupta, H Fattah, R Ayalon, J Kidd… - Clinical …, 2016 - Wiley Online Library
Previous studies that have assessed the association of pre‐transplant antiphospholipase A2
receptor autoantibody (PLA 2R‐Ab) concentration with a recurrence of membranous …

The pathogenesis of membranous nephropathy: evolution and revolution

RJ Glassock - Current opinion in nephrology and hypertension, 2012 - journals.lww.com
The pathogenesis of membranous nephropathy: evolution and re... : Current Opinion in
Nephrology and Hypertension The pathogenesis of membranous nephropathy: evolution and …

Recurrent membranous nephropathy after kidney transplantation: treatment and long-term implications

A Grupper, LD Cornell, FC Fervenza, LH Beck Jr… - …, 2016 - journals.lww.com
Background Membranous nephropathy (MN) can recur in kidney allografts leading to graft
dysfunction and failure. The aims of these analyses were to assess MN recurrence, clinical …

Anti-phospholipase A2 receptor antibody as prognostic indicator in idiopathic membranous nephropathy

YG Kim, YW Choi, SY Kim, JY Moon, CG Ihm… - American journal of …, 2015 - karger.com
Background: Anti-phospholipase A2 receptor antibody (PLA2R-Ab) is useful in diagnosing
idiopathic membranous nephropathy (IMN). We investigated the clinical relevance of PLA2R …

[HTML][HTML] C3aR-initiated signaling is a critical mechanism of podocyte injury in membranous nephropathy

Q Zhang, S Bin, K Budge, A Petrosyan, V Villani… - JCI insight, 2024 - ncbi.nlm.nih.gov
The deposition of antipodocyte autoantibodies in the glomerular subepithelial space
induces primary membranous nephropathy (MN), the leading cause of nephrotic syndrome …