Biofilm formation is often considered the underlying reason why treatment with an
antimicrobial agent fails and as an estimated 65–80% of all human infections is thought to …

Bacterial biofilms are structured communities of bacterial cells enclosed in a self-produced
polymer matrix that is attached to a surface. Biofilms protect and allow bacteria to survive …

The opportunistic pathogen Pseudomonas aeruginosa causes chronic biofilm infections in
cystic fibrosis patients. During colonization of the lung, P. aeruginosa converts to a mucoid …

Covering: up to the end of 2014 The cyclic dinucleotide c-di-GMP has emerged in the last
decade as a prevalent intracellular messenger that orchestrates the transition between the …

We report that larvae of the wax moth (Galleria mellonella) are susceptible to infection with
the human enteropathogen Yersinia pseudotuberculosis at 37° C. Confocal microscopy …

Many bacteria successfully colonize animals by forming protective biofilms. Molecular
processes that underlie the formation and function of biofilms in pathogenic bacteria are well …

Invertebrate animal models are experimentally tractable and have immunity and disease
symptoms that mirror those of vertebrates. Therefore they are of particular utility in …

Yersinia pestis is transmitted from fleas to rodents when the bacterium develops an
extensive biofilm in the foregut of a flea, starving it into a feeding frenzy, or, alternatively …

Vibrio cholerae is an estuarine bacterium and the human pathogen responsible for the
diarrheal disease cholera. In the environment, arthropods are proposed to be carriers and …

Hallmarks of Yersinia pathogenesis include the ability to form biofilms on surfaces, the ability
to establish close contact with eukaryotic target cells and the ability to hijack eukaryotic cell …