Viral entry mechanisms: human papillomavirus and a long journey from extracellular matrix to the nucleus

M Sapp, M Bienkowska‐Haba - The FEBS journal, 2009 - Wiley Online Library
Papillomaviruses are epitheliotropic non‐enveloped double‐stranded DNA viruses, whose
replication is strictly dependent on the terminally differentiating tissue of the epidermis. They …

[HTML][HTML] Structure, attachment and entry of polyoma-and papillomaviruses

M Sapp, PM Day - Virology, 2009 - Elsevier
Polyoma-(PY) and Papillomavirus (PV) virions have remarkable structural equivalence
although no discernable sequence similarities among the capsid proteins can be detected …

Structure of small virus-like particles assembled from the L1 protein of human papillomavirus 16

XS Chen, RL Garcea, I Goldberg, G Casini… - Molecular cell, 2000 - cell.com
The papillomavirus major late protein, L1, forms the pentameric assembly unit of the viral
shell. Recombinant HPV16 L1 pentamers assemble in vitro into capsid-like structures, and …

Crystal structures of four types of human papillomavirus L1 capsid proteins: understanding the specificity of neutralizing monoclonal antibodies

B Bishop, J Dasgupta, M Klein, RL Garcea… - Journal of Biological …, 2007 - ASBMB
Human papillomaviruses (HPVs) are known etiologic agents of cervical cancer. Vaccines
that contain virus-like particles (VLPs) made of L1 capsid protein from several high risk HPV …

Life context of pharmacological academic performance enhancement among university students–a qualitative approach

E Hildt, K Lieb, AG Franke - BMC medical ethics, 2014 - Springer
Background Academic performance enhancement or cognitive enhancement (CE) via
stimulant drug use has received increasing attention. The question remains, however …

Induction of autoantibodies to mouse CCR5 with recombinant papillomavirus particles

B Chackerian, DR Lowy… - Proceedings of the …, 1999 - National Acad Sciences
The vertebrate immune system has evolved to respond vigorously to microbial infection but
to ignore self-antigens. Evidence has emerged that B cell responses to viruses are initiated …

Hybrid papillomavirus L1 molecules assemble into virus-like particles that reconstitute conformational epitopes and induce neutralizing antibodies to distinct HPV …

ND Christensen, NM Cladel, CA Reed, LR Budgeon… - Virology, 2001 - Elsevier
Human papillomavirus (HPV) hybrid virus-like particles (VLPs) were prepared using
complementary regions of the major capsid L1 proteins of HPV-11 and-16. These hybrid L1 …

Identification of two cross-neutralizing linear epitopes within the L1 major capsid protein of human papillomaviruses

AL Combita, A Touzé, L Bousarghin… - Journal of …, 2002 - Am Soc Microbiol
The neutralizing activities of polyclonal antibodies and monoclonal antibodies (MAbs)
obtained by immunization of mice with L1 virus-like particles (VLPs) were investigated by …

Characterization of a major neutralizing epitope on human papillomavirus type 16 L1

WI White, SD Wilson, FJ Palmer-Hill, RM Woods… - Journal of …, 1999 - Am Soc Microbiol
Persistent infection with human papillomavirus type 16 (HPV-16) is strongly associated with
the development of cervical cancer. Neutralizing epitopes present on the major coat protein …

Characterization of a human papillomavirus type 16 variant-dependent neutralizing epitope

RB Roden, A Armstrong, P Haderer… - Journal of …, 1997 - Am Soc Microbiol
We have determined that three type-specific and conformationally dependent monoclonal
antibodies, H16. E70, H16. U4, and H16. V5, neutralize pseudotype human papillomavirus …