[HTML][HTML] 2023 update on sepsis and septic shock in adult patients: management in the emergency department
Background: Sepsis/septic shock is a life-threatening and time-dependent condition that
requires timely management to reduce mortality. This review aims to update physicians with …
requires timely management to reduce mortality. This review aims to update physicians with …
[HTML][HTML] Bloodstream infections in critically ill patients: an expert statement
Bloodstream infection (BSI) is defined by positive blood cultures in a patient with systemic
signs of infection and may be either secondary to a documented source or primary—that is …
signs of infection and may be either secondary to a documented source or primary—that is …
Surviving sepsis campaign: international guidelines for management of sepsis and septic shock 2021
Sepsis is life-threatening organ dysfunction caused by a dysregulated host response to
infection (1). Sepsis and septic shock are major healthcare problems, impacting millions of …
infection (1). Sepsis and septic shock are major healthcare problems, impacting millions of …
[HTML][HTML] Epidemiology and outcomes of hospital-acquired bloodstream infections in intensive care unit patients: the EUROBACT-2 international cohort study
Purpose In the critically ill, hospital-acquired bloodstream infections (HA-BSI) are associated
with significant mortality. Granular data are required for optimizing management, and …
with significant mortality. Granular data are required for optimizing management, and …
Prevalence of antibiotic-resistant pathogens in culture-proven sepsis and outcomes associated with inadequate and broad-spectrum empiric antibiotic use
C Rhee, SS Kadri, JP Dekker, RL Danner… - JAMA network …, 2020 - jamanetwork.com
Importance Broad-spectrum antibiotics are recommended for all patients with suspected
sepsis to minimize the risk of undertreatment. However, little is known regarding the net …
sepsis to minimize the risk of undertreatment. However, little is known regarding the net …
Antibiotic resistance—the need for global solutions
The causes of antibiotic resistance are complex and include human behaviour at many
levels of society; the consequences affect everybody in the world. Similarities with climate …
levels of society; the consequences affect everybody in the world. Similarities with climate …
[HTML][HTML] Rationalizing antimicrobial therapy in the ICU: a narrative review
The massive consumption of antibiotics in the ICU is responsible for substantial ecological
side effects that promote the dissemination of multidrug-resistant bacteria (MDRB) in this …
side effects that promote the dissemination of multidrug-resistant bacteria (MDRB) in this …
[HTML][HTML] Diagnosis of ventilator-associated pneumonia in critically ill adult patients—a systematic review and meta-analysis
The accuracy of the signs and tests that clinicians use to diagnose ventilator-associated
pneumonia (VAP) and initiate antibiotic treatment has not been well characterized. We …
pneumonia (VAP) and initiate antibiotic treatment has not been well characterized. We …
[HTML][HTML] Antibiotic stewardship in the intensive care unit
CE Luyt, N Bréchot, JL Trouillet, J Chastre - Critical care, 2014 - Springer
The rapid emergence and dissemination of antimicrobial-resistant microorganisms in ICUs
worldwide constitute a problem of crisis dimensions. The root causes of this problem are …
worldwide constitute a problem of crisis dimensions. The root causes of this problem are …
Infectious Diseases Society of America position paper: recommended revisions to the national severe sepsis and septic shock early management bundle (SEP-1) …
C Rhee, K Chiotos, SE Cosgrove… - Clinical Infectious …, 2021 - academic.oup.com
Abstract The Centers for Medicare & Medicaid Services' Severe Sepsis and Septic Shock
Early Management Bundle (SEP-1) measure has appropriately established sepsis as a …
Early Management Bundle (SEP-1) measure has appropriately established sepsis as a …