Pulmonary infections caused by the mould pathogen Aspergillus fumigatus are a major
cause of morbidity and mortality globally. Compromised lung defences arising from …

Morbidity, mortality and economic burden caused by chronic obstructive pulmonary disease
(COPD) is a significant global concern. Surprisingly, COPD is already the third leading …

Background The mucolytic and antioxidant effects of N-acetylcysteine (NAC) may have great
value in COPD treatment. However, beneficial effects have not been confirmed in clinical …

Many lung diseases, such as severe asthma, chronic obstructive pulmonary disease
(COPD), cystic fibrosis (CF), bronchiectasis and infiltrative pulmonary diseases are …

Background The p38 MAPK pathway seems to be involved in pathogenesis of chronic
obstructive pulmonary disease (COPD). Losmapimod is a potent and selective inhibitor of …

Background Lung volume reduction surgery (LVRS) performed to treat patients with severe
diffuse emphysema was reintroduced in the nineties. Lung volume reduction surgery aims to …

Background Intrabronchial valve placement for endoscopic lung volume reduction is used
for patients with severe lung emphysema. Different treatment approaches are unilateral …

This review is the summary of a workshop on the role of distal airways in chronic obstructive
pulmonary disease (COPD), which took place in 2009 in Vence, France. The evidence …

Introduction The main white blood cell populations, neutrophils and lymphocytes, are
involved in the pathophysiology of chronic obstructive pulmonary disease (COPD). We …

The metabolic syndrome is found to be more frequent in chronic obstructive pulmonary
disease (COPD). The presence of inflammatory markers in circulation, sputum, and broncho …