HSP70: an alarmin that does not induce high rates of preterm birth but does cause adverse neonatal outcomes

G Schwenkel, R Romero, R Slutsky… - The Journal of …, 2021 - Taylor & Francis
Objective Preterm labor and birth are strongly associated with sterile intra-amniotic
inflammation, a clinical condition that is proposed to be initiated by danger signals, or …

[HTML][HTML] Rescuing fertility during COVID-19 infection: exploring potential pharmacological and natural therapeutic approaches for comorbidity, by focusing on NLRP3 …

E Hosseini, HR Kohan-Ghadr, M Bazrafkan… - Journal of assisted …, 2023 - Springer
The respiratory system was primarily considered the only organ affected by Coronavirus
disease 2019 (COVID-19). As the pandemic continues, there is an increasing concern from …

The immunophenotype of decidual macrophages in acute atherosis

N Gill, Y Leng, R Romero, Y Xu… - American Journal of …, 2019 - Wiley Online Library
Problem Acute atherosis is a uteroplacental arterial lesion that is associated with pregnancy
complications such as preeclampsia and preterm birth, the latter being the leading cause of …

[HTML][HTML] Telomeres and replicative cellular aging of the human placenta and chorioamniotic membranes

TP Lai, M Simpson, K Patel, S Verhulst, J Noh… - Scientific reports, 2021 - nature.com
Recent hypotheses propose that the human placenta and chorioamniotic membranes
(CAMs) experience telomere length (TL)-mediated senescence. These hypotheses are …

Prostaglandin and prostamide concentrations in amniotic fluid of women with spontaneous labor at term with and without clinical chorioamnionitis

HN Peiris, R Romero, K Vaswani… - … and Essential Fatty …, 2020 - Elsevier
Abstract Objective Prostaglandins (PGs) are considered universal mediators for the process
of physiological parturition. This is based on observations that amniotic fluid concentrations …

Surfactant-secreted phospholipase A2 interplay and respiratory outcome in preterm neonates

D De Luca, S Shankar-Aguilera… - … of Physiology-Lung …, 2020 - journals.physiology.org
Secreted phospholipase A2 hydrolyzes surfactant phospholipids and is crucial for the
inflammatory cascade; preterm neonates are treated with exogenous surfactant, but the …

Membrane inflammasome activation by choriodecidual Ureaplasma parvum infection without intra-amniotic infection in a Non-Human Primate model

S Tripathy, I Burd, MA Kelleher - Biology of Reproduction, 2024 - academic.oup.com
Intrauterine infection is a significant cause of neonatal morbidity and mortality. Ureaplasma
parvum is a microorganism commonly isolated from cases of preterm birth and preterm …

[HTML][HTML] Prematurely delivering mothers show reductions of lachnospiraceae in their gut microbiomes

R Yang, X Li, Z Ying, Z Zhao, Y Wang, Q Wang… - BMC microbiology, 2023 - Springer
Background Preterm birth is the leading cause of perinatal morbidity and mortality. Despite
evidence shows that imbalances in the maternal microbiome associates to the risk of …

Transcription factors regulated by cAMP in smooth muscle of the myometrium at human parturition

JKH Li, PF Lai, RM Tribe… - Biochemical Society …, 2021 - portlandpress.com
Cyclic adenosine monophosphate (cAMP) contributes to maintenance of a quiescent
(relaxed) state in the myometrium (ie uterine smooth muscle) during pregnancy, which most …

Преждевременные роды: прошлые ограничения и новые возможности

КА Горина, ЗС Ходжаева, ДМ Белоусов… - Акушерство и …, 2020 - elibrary.ru
Проведены поиск и анализ данных мировой литературы, посвященной исследованию
инфекционновоспалительного фактора как ведущего в генезе преждевременных …