Neurocognitive deficits are evident both in established schizophrenia and bipolar disorder
(BP). However, it has been suggested that schizophrenia, but not BP, is characterized by …

Objectives Bipolar disorder (BD) is a debilitating illness, the psychopathology of which is
associated with aberrant structural and functional differences in the brain. Despite the many …

Despite decades of research, the pathophysiology of bipolar disorder (BD) is still not well
understood. Structural brain differences have been associated with BD, but results from …

Given the global burden of psychotic disorders, the identification of patients with early-onset
psychosis (EOP; that is, onset before the age of 18) at higher risk of adverse outcome should …

Objectives The profiles of cortical abnormalities in schizophrenia and bipolar disorder, and
how far they resemble each other, have only been studied to a limited extent. The aim of this …

There is a gap in knowledge regarding the polygenic underpinnings of brain anomalies
observed in youth bipolar disorder (BD). This study examined the association of a polygenic …

Objective: To highlight the changes in the frontal lobe of the human brain in people with
schizophrenia. Methods: This was a qualitative review of the literature. Results: Many …

Early‐onset psychosis disorders are serious mental disorders arising before the age of 18
years. Here, we investigate the largest neuroimaging dataset, to date, of patients with early …

Background Studies on longitudinal brain volume changes in patients with early-onset
psychosis (EOP) are particularly valuable for understanding the neurobiological basis of …

Brain volume and thickness abnormalities have been reported in first-episode psychosis
(FEP). However, it is unclear if and how they are modulated by brain developmental stage …