The renin-angiotensin-aldosterone system (RAAS) is central to the pathogenesis of
hypertension, cardiovascular disease, and kidney disease. Evidence supports various …

With the growing worldwide obesity epidemic, obesity, type 2 diabetes mellitus and
hypertension leading to premature cardiovascular events, are increasingly prevalent …

Aims/hypothesis We investigated whether therapy with the entire daily dose of≥ 1
hypertension medications at bedtime exerts greater reduction in the risk of new-onset …

Abstract Treatment with cisplatin is associated with dose‐limiting side effects, mainly
nephrotoxicity. On the other hand, nebivolol, a β1‐adrenoceptor antagonist, exhibits …

53 химеризма (возникновение аутоиммунных реакций в связи с проникновением клеток
плода в организм матери). С другой стороны, при сопоставлении пациентов с впервые …

Background and Objectives: Hypertension is a widely prevalent con-dition of elevated blood
pressure (BP) and is the leading risk factor for the development of cardiovascular disease …

Abstract β‐Blockers are widely used in the treatment of cardiovascular disease and act by
antagonizing the effects of adrenaline (epinephrine) and noradrenaline (norepinephrine) on …

Ревматоидный артрит (РА)-хроническое аутоиммунное заболевание с доказано
высоким риском развития сердечно-сосудистых заболеваний (ССЗ), увеличение …

Background. Nitric oxide (NO) deficiency contributes to chronic kidney disease (CKD)
progression and hypertension. The β-blocker, nebivolol (N), also enhances NO production …

Background Irbesartan has been reported to have beneficial effects on glucose/lipid
metabolism in addition to an antihypertensive effect; however, such effects have not been …