Working memory (WM) extends the duration over which information is available for
processing. Given its importance in supporting a wide-array of high level cognitive abilities …

Ketamine is a dissociative anesthetic drug, which has more recently emerged as a rapid-
acting antidepressant. When acutely administered at subanesthetic doses, ketamine causes …

Frontal and parietal cortex are implicated in economic decision-making, but their causal
roles are untested. Here we silenced the frontal orienting field (FOF) and posterior parietal …

Voluntary attention selects behaviorally relevant signals for further processing while filtering
out distracter signals. Neural correlates of voluntary visual attention have been reported …

The newly evolved prefrontal cortex (PFC) generates goals for “top-down” control of
behavior, thought, and emotion. However, these circuits are especially vulnerable to …

The activity of neurons in the primate lateral prefrontal cortex (LPFC) is strongly modulated
by visual attention. Such a modulation has mostly been documented by averaging the …

Recent advances in connectomics and neurophysiology make it possible to probe whole-
brain mechanisms of cognition and behavior. We developed a large-scale model of the …

The primate lateral prefrontal cortex (LPFC) encodes visual stimulus features while they are
perceived and while they are maintained in working memory. However, it remains unclear …

Highlights•In tasks of information demand, participants explicitly request information.•The
tasks prompt a view of priority as a cognitive state that facilitates information …

The statistical structure of intrinsic parietal and parieto-frontal connectivity in monkeys was
studied through hierarchical cluster analysis. Based on their inputs, parietal and frontal …