The discovery of regulated cell death processes has enabled advances in cancer treatment.
In the past decade, ferroptosis, an iron-dependent form of regulated cell death driven by …

Patients with cancer are at greater risk of developing depression in comparison to the
general population and this is associated with serious adverse effects, such as poorer …

Patients with glioblastoma (GBM) have poor prognosis and limited treatment options, largely
due to therapy resistance upon the induction of apoptosis. Ferroptosis emerges as a …

Ferroptosis is a novel form of programmed cell death morphologically, genetically, and
biochemically distinct from other cell death pathways and characterized by the accumulation …

Breast cancer is the most common cancer among women and is considered a developed
country disease. Moreover, is a heterogenous disease, existing different types and stages of …

In recent years, the incidence of different types of cancer and patient survival have been
rising, as well as their prevalence. The increase in survival in recent years exposes the …

Multiple myeloma (MM) cells derive proliferative signals from the bone marrow (BM)
microenvironment via exosomal crosstalk. Therapeutic strategies targeting this crosstalk are …

In the past decade, the rise of immunometabolism has fundamentally reshaped the face of
immunology. As the functions and properties of many (immuno) metabolites have now been …

Background & Aims Many differentiated epithelial cell types are able to reprogram in
response to tissue damage. Although reprogramming represents an important physiological …

Abstract xCT (Slc7a11), the specific subunit of the cystine/glutamate antiporter system x c-, is
present in the brain and on immune cells, where it is known to modulate behavior and …