Clinical efficacy of intranasal administration of oxytocin is increasingly explored in autism
spectrum disorder, but to date, the biological effects of chronic administration regimes on …

Oxytocin is a potential therapeutic for the core symptoms of autism spectrum disorder (ASD),
which is currently untreatable with pharmacotherapy. Previous clinical trials of a single dose …

The dopamine D2 and D3 receptors are implicated in schizophrenia and its
pharmacological treatments. These receptors undergo intracellular trafficking processes that …

Social deficits are a hallmark feature of autism spectrum disorder (ASD) and related
developmental syndromes. Although there is no standard treatment for social dysfunction …

In socially monogamous titi monkeys, involuntary separation from a pair mate can produce
behavioral distress and increased cortisol production. The neuropeptide oxytocin (OXT) is …

In the face of the alarming prevalence of obesity and its associated metabolic impairments, it
is of high basic and clinical interest to reach a complete understanding of the central …

Our understanding of the oxytocin system has been built over the last 70 years by the work
of hundreds of scientists, reported in thousands of papers. Here, we construct a map to that …

ADHD, schizophrenia and bipolar disorder are psychiatric diseases with a strong genetic
component which share dopaminergic alterations. Dopamine transporter (DAT) genetics …

No approved pharmacological intervention currently exists to address the core symptoms of
autism spectrum disorder, a prevalent neurodevelopmental condition. However, there is a …

Oxytocin (OT) is a prominent regulator of many aspects of mammalian social behavior and
stored in large dense-cored vesicles (LDCVs) in hypothalamic neurons. It is released in …