Extracellular vesicles (EVs) represent a novel mechanism of intercellular communication as
vehicles for intercellular transfer of functional membrane and cytosolic proteins, lipids, and …

The tetraspanin web represents a new concept of molecular interactions in the immune
system. Whereas most surface immune-modulating molecules involve receptor–ligand …

Exciting new findings have emerged about the structure, function and biochemistry of
tetraspanin proteins. Five distinct tetraspanin regions have now been delineated linking …

Hepatitis C Virus (HCV) infection is a global public health problem affecting over 160 million
individuals worldwide. Its symptoms include chronic hepatitis, liver cirrhosis and …

Tetraspanin KAI1/CD82 is a wide-spectrum tumor metastasis suppressor. KAI1/CD82
suppresses tumor metastasis by primarily inhibiting cancer cell motility and invasiveness. In …

Hepatitis C virus (HCV) infection afflicts more than 170 million people worldwide, with the
great majority of patients with acute hepatitis C developing chronic HCV infection. It can …

Tetraspanin uroplakins (UPs) Ia and Ib, together with their single-spanning transmembrane
protein partners UP II and IIIa, form a unique crystalline 2D array of 16-nm particles covering …

The tetraspanins are a broadly expressed superfamily of transmembrane glycoproteins with
over 30 members found in humans and with homologues conserved through distantly …

Invasion of hepatocytes by Plasmodium sporozoites is a prerequisite for establishment of a
malaria infection, and thus represents an attractive target for anti-malarial interventions. Still …

Background & Aims Assembly of infectious hepatitis C virus (HCV) particles is known to
involve host lipoproteins, giving rise to unique lipo-viro-particles (LVPs), but proteome …