Herpes simplex encephalitis (HSE) is the most common form of acute viral encephalitis in
industrialized countries. Type I interferon (IFN) is important for control of herpes simplex …

Stem cell-based regenerative therapies hold great potential for the treatment of
degenerative disorders such as Parkinson's disease (PD). We recently reported the repair …

Neural stem cells constitute a promising source of cells for transplantation in Parkinson's
disease, but a protocol for controlled dopaminergic differentiation is not yet available. Here …

Parkinson's disease (PD) affects the motor system through the degeneration of the
dopaminergic neurons of the substantia nigra. The use of human embryonic stem cell …

Parkinson's disease (PD) is characterized by the selective loss of midbrain dopamine
neurons. Neural transplantation with fetal dopamine neurons can be an effective therapy for …

Chronic rhinosinusitis with nasal polyps is considered a subgroup of chronic rhinosinusitis
and a significant health problem, but the pathogenesis remains unclear to date. Therefore …

The rostral migratory stream (RMS) is the main pathway by which newly born subventricular
zone (SVZ) cells reach the olfactory bulb (OB) in rodents. This migration has been well …

Muscle-derived stem cells reside in the skeletal muscle tissues and are known for their
multipotency to differentiate toward the mesodermal lineage. Recent studies have …

Background Targeted differentiation of stem cells is mainly achieved by the sequential
administration of defined growth factors and cytokines, although these approaches are quite …

Earlier published research showed that cord blood-derived multipotent stem cells (CB-SCs)
exhibited the intrinsic expression of specific transcription factors (eg, En1, Nurr1 and Wnt1) …