Advances in the field of intranasal oxytocin research: lessons learned and future directions for clinical research

DS Quintana, A Lischke, S Grace, D Scheele… - Molecular …, 2021 - nature.com
Reports on the modulatory role of the neuropeptide oxytocin on social cognition and
behavior have steadily increased over the last two decades, stimulating considerable …

The power of a positive human–animal relationship for animal welfare

JL Rault, S Waiblinger, X Boivin… - Frontiers in veterinary …, 2020 - frontiersin.org
Domestic animals often seek and enjoy interacting with humans. Positive human–animal
relationships can elicit positive emotions and other positive welfare outcomes. Nevertheless …

Vascular RAGE transports oxytocin into the brain to elicit its maternal bonding behaviour in mice

Y Yamamoto, M Liang, S Munesue, K Deguchi… - Communications …, 2019 - nature.com
Oxytocin sets the stage for childbirth by initiating uterine contractions, lactation and maternal
bonding behaviours. Mice lacking secreted oxcytocin (Oxt−/−, Cd38−/−) or its receptor …

The role of oxytocin in regulation of appetitive behaviour, body weight and glucose homeostasis

EA Lawson, PK Olszewski, A Weller… - Journal of …, 2020 - Wiley Online Library
Obesity and its associated complications have reached epidemic proportions in the USA
and also worldwide, highlighting the need for new and more effective treatments. Although …

Be kind to others: Prosocial behaviours and their implications for animal welfare

JL Rault - Applied Animal Behaviour Science, 2019 - Elsevier
Social interactions are central to the health and psychological well-being of domestic
animals. Until now, research has overwhelmingly focused on negative social behaviours …

Interactions between the κ opioid system, corticotropin-releasing hormone and oxytocin in partner loss

KL Bales, FD Rogers - Philosophical Transactions of the …, 2022 - royalsocietypublishing.org
Selective adult social attachments, or 'pair bonds', represent central relationships for
individuals in a number of social species, including humans. Loss of a pair mate has …

Oxytocin as an indicator of psychological and social well-being in domesticated animals: a critical review

JL Rault, M van den Munkhof… - Frontiers in …, 2017 - frontiersin.org
Oxytocin is often portrayed as a hormone specific to social behavior, reflective of positive
welfare states, and linked to mental states. Research on oxytocin in domesticated animal …

Crosstalk between schizophrenia and metabolic syndrome: The role of oxytocinergic dysfunction

KK Goh, CYA Chen, TH Wu, CH Chen… - International journal of …, 2022 - mdpi.com
The high prevalence of metabolic syndrome in persons with schizophrenia has spurred
investigational efforts to study the mechanism beneath its pathophysiology. Early psychosis …

Salivary oxytocin in pigs, cattle, and goats during positive human-animal interactions

S Lürzel, L Bückendorf, S Waiblinger… - Psychoneuroendocrinology, 2020 - Elsevier
Research on oxytocin (OT) has provided crucial insight into the neuroendocrine
mechanisms of social behavior and human-animal interactions. Nonetheless, this peptide …

Intranasal administration for pain: oxytocin and other polypeptides

VN Bharadwaj, AZ Tzabazis, M Klukinov, NA Manering… - Pharmaceutics, 2021 - mdpi.com
Pain, particularly chronic pain, remains one of the most debilitating and difficult-to-treat
conditions in medicine. Chronic pain is difficult to treat, in part because it is associated with …