[HTML][HTML] Antioxidant and oxidative stress: a mutual interplay in age-related diseases

BL Tan, ME Norhaizan, WPP Liew… - Frontiers in …, 2018 - frontiersin.org
Aging is the progressive loss of organ and tissue function over time. Growing older is
positively linked to cognitive and biological degeneration such as physical frailty …

Apoptosis and its therapeutic implications in neurodegenerative diseases

NS Erekat - Clinical Anatomy, 2022 - Wiley Online Library
Neurodegenerative disorders are characterized by progressive loss of particular populations
of neurons. Apoptosis has been implicated in the pathogenesis of neurodegenerative …

[HTML][HTML] Antioxidant compounds from edible mushrooms as potential candidates for treating age-related neurodegenerative diseases

GM Liuzzi, T Petraglia, T Latronico, A Crescenzi… - Nutrients, 2023 - mdpi.com
The last century has seen an increase in our life expectancy. As a result, various age-related
diseases, such as neurodegenerative diseases (NDs), have emerged, representing new …

Overview and recent advances in electrochemical sensing of glutathione–A review

M Hanko, Ľ Švorc, A Planková, P Mikuš - Analytica chimica acta, 2019 - Elsevier
The present paper is aimed at providing an overview of the recent advances in the
electrochemical sensing of glutathione (GSH), an important electrochemically and …

Role for the PI3K/Akt/Nrf2 signaling pathway in the protective effects of carnosic acid against methylglyoxal-induced neurotoxicity in SH-SY5Y neuroblastoma cells

MR de Oliveira, GC Ferreira, PF Schuck… - Chemico-biological …, 2015 - Elsevier
Glycation, a process that occurs endogenously and generates advanced glycation end
products (AGEs), presents an important role in cases of neurodegeneration, as for instance …

Glutamate cysteine ligase and the age-related decline in cellular glutathione: The therapeutic potential of γ-glutamylcysteine

G Ferguson, W Bridge - Archives of biochemistry and biophysics, 2016 - Elsevier
A consistent underlying index of aging is a decline in the cellular levels of the tripeptide
glutathione (GSH). GSH is an essential thiol antioxidant produced in the cytosol of all cells …

Do glutathione and copper interact to modify Alzheimer's disease pathogenesis?

T Ho, S Ahmadi, K Kerman - Free Radical Biology and Medicine, 2022 - Elsevier
Alzheimer's disease (AD) is a progressive neurodegenerative disorder first described in
1906 that is currently estimated to impact∼ 40 million people worldwide. Extensive research …

[HTML][HTML] Tri-element nanozyme PtCuSe as an ingenious cascade catalytic machine for the amelioration of Parkinson's disease-like symptoms

H Xu, X Ding, L Li, Q Li, Z Li, H Lin - Frontiers in Bioengineering and …, 2023 - frontiersin.org
Parkinson's disease (PD), as the second most common neurodegenerative disease after
Alzheimer's, has become intractable with the increasing aging global population. The …

[HTML][HTML] Potential of therapeutic small molecules in apoptosis regulation in the treatment of neurodegenerative diseases: An updated review

HG Dailah - Molecules, 2022 - mdpi.com
Neurodegenerative disorders (NDs) include Parkinson's disease (PD), Alzheimer's disease
(AD), Huntington's disease (HD), and amyotrophic lateral sclerosis (ALS) and the common …

[HTML][HTML] Effects of electroacupuncture on urinary metabolome and microbiota in presenilin1/2 conditional double knockout mice

J Gao, N Zhou, M Lu, Q Wang, C Zhao… - Frontiers in …, 2023 - frontiersin.org
Aim The treatment of Alzheimer's disease (AD) is still a worldwide problem due to the
unclear pathogenesis and lack of effective therapeutic targets. In recent years, metabolomic …