Amphisomes are intermediate/hybrid organelles produced through the fusion of endosomes
with autophagosomes within cells. Amphisome formation is an essential step during a …

Depression is prevalent in patients with physical disorders, particularly in those with severe
disorders such as cancer, stroke, and acute coronary syndrome. Depression has an adverse …

Stroke remains a leading cause of adult disability. Some degree of spontaneous behavioral
recovery is usually seen in the weeks after stroke onset. Variability in recovery is substantial …

The mood stabilizers lithium and valproic acid (VPA) are traditionally used to treat bipolar
disorder (BD), a severe mental illness arising from complex interactions between genes and …

Two ETS transcription factors of the Pea3 subfamily are induced in subpopulations of dorsal
root ganglion (DRG) sensory and spinal motor neurons by target-derived factors. Their …

Experience-dependent plasticity shapes postnatal development of neural circuits, but the
mechanisms that refine dendritic arbors, remodel spines, and impair synaptic activity are …

During development, neural networks are established in a highly organized manner, which
persists throughout life. Neurotrophins play crucial roles in the developing nervous system …

Brain-derived neurotrophic factor (BDNF) is best characterized for critical roles in neuronal
survival, differentiation, and synaptic modulation mediated by the TrkB receptor tyrosine …

More Americans are consuming diets higher in saturated fats and refined sugars than ever
before, and based on increasing obesity rates, this is a growing trend among older adults as …

There is significant variation in the way individuals react and respond to extreme stress and
adversity. While some individuals develop psychiatric conditions such as posttraumatic …