Progress in the diagnosis and classification of pituitary adenomas

LV Syro, F Rotondo, A Ramirez, A Di Ieva… - Frontiers in …, 2015 - frontiersin.org
Pituitary adenomas are common neoplasms. Their classification is based upon size,
invasion of adjacent structures, sporadic or familial cases, biochemical activity, clinical …

LncRNA LINC00473 is involved in the progression of invasive pituitary adenoma by upregulating KMT5A via ceRNA-mediated miR-502-3p evasion

J Li, Y Qian, C Zhang, W Wang, Y Qiao, H Song… - Cell death & …, 2021 - nature.com
Long noncoding RNAs (lncRNAs) and their crosstalks with other RNAs have been revealed
to be closely related to tumorigenesis and development, but their role in invasive pituitary …

Circulating Noncoding RNAs in Pituitary Neuroendocrine Tumors—Two Sides of the Same Coin

H Butz - International Journal of Molecular Sciences, 2022 - mdpi.com
Pituitary neuroendocrine tumors (PitNET) are common intracranial neoplasms. While in case
of hormone secreting tumors pituitary hormone measurements can be used for monitoring …

Сytotoxic T lymphocyte-associated protein 4 (CTLA4) is overexpressed in a subset of prolactin-and growth hormone-secreting pituitary adenomas

E Sabini, A Khan, P Caturegli - Endocrine-related cancer, 2024 - erc.bioscientifica.com
Cytotoxic T lymphocyte-associated protein 4 (CTLA4), a negative regulator typically
expressed on the surface of T lymphocytes, is targeted by immunotherapy in patients with an …

Predictive modeling for pituitary adenomas: single center experience in 501 consecutive patients

AL Pappy, A Savinkina, C Bicknese, S Neill… - Pituitary, 2019 - Springer
Background Personalized postoperative management of patients with pituitary adenomas
requires an early risk stratification system. Methods We reviewed 501 cases operated …

Analysis of related factors of tumor recurrence or progression after transnasal sphenoidal surgical treatment of large and giant pituitary adenomas and establish a …

Y Chen, F Cai, J Cao, F Gao, Y Lv, Y Tang… - Frontiers in …, 2021 - frontiersin.org
Background Pituitary adenoma (PA) is a benign neuroendocrine tumor caused by
adenohypophysial cells, and accounts for 10%-20% of all primary intracranial tumors. The …

ACTH-secreting pituitary carcinoma with TP53, NF1, ATRX and PTEN mutations Case report and review of the literature

P Sumislawski, R Rotermund, S Klose, A Lautenbach… - Endocrine, 2022 - Springer
Pituitary carcinoma (PC) is a very rare tumor entity of the sella turcica, representing 0.1–
0.5% of all PitNETs tumors [1–5]. Based on the WHO Classification, it is defined as pituitary …

Mammosomatotroph and mixed somatotroph-lactotroph adenoma in acromegaly: A retrospective study with long-term follow-up

L Lv, Y Jiang, S Yin, Y Hu, C Chen, W Ma, S Jiang… - Endocrine, 2019 - Springer
Purpose Although well-documented from pathological aspect, the clinical features and
outcomes of acromegaly with mammosomatotroph (MSA) and mixed somatotroph-lactotroph …

Homeostatic and tumourigenic activity of SOX2+ pituitary stem cells is controlled by the LATS/YAP/TAZ cascade

EJ Lodge, A Santambrogio, JP Russell, P Xekouki… - Elife, 2019 - elifesciences.org
SOX2 positive pituitary stem cells (PSCs) are specified embryonically and persist throughout
life, giving rise to all pituitary endocrine lineages. We have previously shown the activation …

Targeting the tumor immune microenvironment could become a potential therapeutic modality for aggressive pituitary adenoma

Z Yang, X Tian, K Yao, Y Yang, L Zhang, N Liu, C Yan… - Brain Sciences, 2023 - mdpi.com
Object: This study aimed to explore the relationship between the aggressiveness and
immune cell infiltration in pituitary adenoma (PA) and to provide the basis for immuno …