[PDF][PDF] Globalna analiza ilościowa białek zaangażowanych w patogenezę proteinopatii TDP-43

A Karpiński - repozytorium.uw.edu.pl
Świadom odpowiedzialności prawnej oświadczam, że niniejsza rozprawa doktorska została
napisana przeze mnie samodzielnie i nie zawiera treści uzyskanych w sposób niezgodny z …

Molecular mechanisms of C9orf72-linked frontotemporal dementia and amyotrophic lateral sclerosis

F Riemslagh - 2019 - repub.eur.nl
Frontotemporal dementia (FTD) and amyotrophic lateral sclerosis (ALS) are two devastating
neurological disorders that share clinical, genetic and pathological overlap. The discovery of …

Nucleocytoplasmic Transport Defects: Cause or Consequence in Neurodegeneration and Aging?

İ Armağan, E Ulupınar - Türk Tıp Öğrencileri Araştırma Dergisi, 2020 - dergipark.org.tr
Nucleus is the most important organelle of a cell playing a critical role in the regulation of
gene expression. The nuclear pore complexes (NPCs) spanning the NE are the largest …

Vpliv genov povezanih z amiotrofično lateralno sklerozo na biokemijske lastnosti in celično lokalizacijo proteina TDP-43

A Bajc Česnik - 2020 - repozitorij.uni-lj.si
Uvod: Amiotrofična lateralna skleroza (ALS) je smrtonosna napredujoča
nevrodegenerativna bolezen, za katero so značilni citoplazemski skupki proteinov v …

Environmental and Genetic Influence on Cognition in ALS-FTD Spectrum Disease

K Placek - 2020 - search.proquest.com
Amyotrophic lateral sclerosis (ALS) and frontotemporal degeneration (FTD) are earlier-
onset, fatal neurodegenerative diseases that progressively rob affected individuals of their …

[PDF][PDF] BRAIN COMMUNICATIONS AIN COMMUNICATIONS

JC Bridi, E Bereczki, SK Smith, GM Pocas, B Kottler… - eprints.whiterose.ac.uk
Abbreviations: AZ ¼ active zone; CSP ¼ cysteine string protein; DA ¼ dopaminergic; DART
¼ Drosophila ARousal Tracking system; DLB ¼ dementia with Lewy bodies; iSIM ¼ instant …

[PDF][PDF] Cytosolic calcium regulates cytoplasmic accumulation of TDP-43 through Calpain-A and Importin a3

JH Park, CG Chung, SS Park, D Lee, KM Kim, Y Jeong… - researchgate.net
Cytoplasmic accumulation of TDP-43 in motor neurons is the most prominent pathological
feature in amyotrophic lateral sclerosis (ALS). A feedback cycle between nucleocytoplasmic …

Channel nuclear pore protein 54 directs sexual differentiation and neuronal wiring required for female reproductive behaviors in Drosophila

IU Haussmann, MP Nallasivan, D Scocchia, A Civetta… - bioRxiv, 2019 - biorxiv.org
The post-mating response induced by male-derived sex-peptide in Drosophila females is a
well-established model to elucidate how complex innate behaviors are hard-wired into the …

Inter-and Intracellular Resistance and Vulnerability in Motor Neuron Diseases

J Nijssen - 2020 - search.proquest.com
Amyotrophic lateral sclerosis (ALS) and spinal muscular atrophy (SMA) are fatal diseases
presenting with degeneration and loss of lower motor neurons in the brainstem and spinal …

[PDF][PDF] Population-based Genotype-phenotype Correlation to Stratify Incident Cases of Motor Neurone Disease in Scotland, from 2015-2017

DJ Leighton - 2020 - core.ac.uk
Background: Motor neurone disease (MND) refers to a spectrum of rapidly progressive
neurodegenerative diseases for which there remains no cure. A recognised and crucial …