[HTML][HTML] New therapies for advanced thyroid cancer

D Laha, N Nilubol, M Boufraqech - Frontiers in endocrinology, 2020 - frontiersin.org
Thyroid cancer is the most common endocrine cancer. The discovery of new biomarkers for
thyroid cancer has significantly improved the understanding of the molecular pathogenesis …

A patent review on efficient strategies for the total synthesis of pazopanib, regorafenib and lenvatinib as novel anti-angiogenesis receptor tyrosine kinase inhibitors for …

P Shiri, S Ramezanpour, AM Amani, W Dehaen - Molecular diversity, 2022 - Springer
Angiogenesis is an important and interesting scientific subject in the area of malignant
tumours. Current research importance and interest are directed in connection to blood …

Cabozantinib for radioiodine-refractory differentiated thyroid cancer (COSMIC-311): a randomised, double-blind, placebo-controlled, phase 3 trial

MS Brose, B Robinson, SI Sherman… - The Lancet …, 2021 - thelancet.com
Background Patients with radioiodine-refractory differentiated thyroid cancer (DTC)
previously treated with vascular endothelial growth factor receptor (VEGFR)-targeted …

[HTML][HTML] Optical diagnostic imaging and therapy for thyroid cancer

C Shao, Z Li, C Zhang, W Zhang, R He, J Xu, Y Cai - Materials Today Bio, 2022 - Elsevier
Thyroid cancer, as one of the most common endocrine cancers, has seen a surge in
incidence in recent years. This is most likely due to the lack of specificity and accuracy of its …

[HTML][HTML] Clinical significance of oxidative stress markers as angioinvasion and metastasis indicators in papillary thyroid cancer

A Buczyńska, I Sidorkiewicz, M Kościuszko… - Scientific Reports, 2023 - nature.com
Angioinvasion remains the important prognostic feature in papillary thyroid cancer (PTC)
patients. Literature data indicates several markers that may be associated with oxidative …

FDA approval summary: cabozantinib for differentiated thyroid cancer

ES Duke, AK Barone, S Chatterjee… - Clinical Cancer …, 2022 - AACR
Abstract On September 17, 2021, the FDA approved cabozantinib (Cabometyx; Exelixis,
Inc.) for the treatment of adult and pediatric patients 12 years of age and older with locally …

[HTML][HTML] Dual targeting of MAPK and PI3K pathways unlocks redifferentiation of Braf-mutated thyroid cancer organoids

H Lasolle, A Schiavo, A Tourneur, P Gillotay… - Oncogene, 2024 - nature.com
Thyroid cancer is the most common endocrine malignancy and several genetic events have
been described to promote the development of thyroid carcinogenesis. Besides the effects of …

Efficacy and safety of pembrolizumab monotherapy in patients with advanced thyroid cancer in the phase 2 keynote‐158 study

DY Oh, A Algazi, J Capdevila, F Longo, W Miller Jr… - Cancer, 2023 - Wiley Online Library
Background The authors report results from the thyroid carcinoma cohort of the multicohort
phase 2 KEYNOTE‐158 study (NCT02628067), which evaluated pembrolizumab …

[HTML][HTML] The relationship between thyrotropin serum concentrations and thyroid carcinoma

X Zhang, L Tian, D Teng, W Teng - Cancers, 2023 - mdpi.com
Simple Summary Thyroid-stimulating hormone (TSH) plays a role in the regulation of thyroid
hormones and is an important indicator for assessing thyroid function. Thyroid cancer (TC) is …

[HTML][HTML] Improving the diagnosis of thyroid cancer by machine learning and clinical data

NM Xi, L Wang, C Yang - Scientific reports, 2022 - nature.com
Thyroid cancer is a common endocrine carcinoma that occurs in the thyroid gland. Much
effort has been invested in improving its diagnosis, and thyroidectomy remains the primary …