[HTML][HTML] Understanding kratom use: a guide for healthcare providers
Kratom (Mitragyna speciosa Korth., Rubiaceae) is a plant native to Southeast Asia, where it
has been used for centuries as a mild stimulant and as medicine for various ailments. More …
has been used for centuries as a mild stimulant and as medicine for various ailments. More …
[HTML][HTML] Kratom—pharmacology, clinical implications, and outlook: a comprehensive review
SC Eastlack, EM Cornett, AD Kaye - Pain and therapy, 2020 - Springer
Kratom, or Mitragyna, is a tropical plant indigenous to Southeast Asia, with unique
pharmacological properties. It is commonly consumed by preparing the leaves into …
pharmacological properties. It is commonly consumed by preparing the leaves into …
[HTML][HTML] Chemical composition and biological effects of kratom (Mitragyna speciosa): In vitro studies with implications for efficacy and drug interactions
The safety and efficacy of kratom (Mitragyna speciosa) for treatment of pain is highly
controversial. Kratom produces more than 40 structurally related alkaloids, but most studies …
controversial. Kratom produces more than 40 structurally related alkaloids, but most studies …
Prevalence and description of kratom (Mitragyna speciosa) use in the United States: a cross‐sectional study
J Schimmel, E Amioka, K Rockhill, CM Haynes… - …, 2021 - Wiley Online Library
Background and aims Mitragyna speciosa ('kratom') contains mu opioid partial agonists. It is
widely available, and occasionally used as a home remedy for opioid use disorder. The …
widely available, and occasionally used as a home remedy for opioid use disorder. The …
Therapeutic benefit with caveats?: Analyzing social media data to understand the complexities of kratom use
Background Mitragyna speciosa, referred to as “kratom”, is increasingly used in the United
States for self-treating pain, psychiatric, and substance use disorder symptoms. It is used by …
States for self-treating pain, psychiatric, and substance use disorder symptoms. It is used by …
Pharmacokinetics of eleven kratom alkaloids following an oral dose of either traditional or commercial kratom products in rats
SH Kamble, EC Berthold, TI King… - Journal of natural …, 2021 - ACS Publications
Kratom, Mitragyna speciosa Korth., is being widely consumed in the United States for pain
management and the reduction of opioid withdrawal symptoms. The central nervous system …
management and the reduction of opioid withdrawal symptoms. The central nervous system …
A systematic review of (pre) clinical studies on the therapeutic potential and safety profile of kratom in humans
E Prevete, KPC Kuypers, EL Theunissen… - Human …, 2022 - Wiley Online Library
Abstract Introduction Kratom (Mitragyna speciosa) is a tropical plant traditionally used as an
ethnomedicinal remedy for several conditions in South East Asia. Despite the increased …
ethnomedicinal remedy for several conditions in South East Asia. Despite the increased …
Prevalence and characteristics of self-reported kratom use in a representative US general population sample
JR Covvey, SM Vogel, AM Peckham… - Journal of addictive …, 2020 - Taylor & Francis
Abstract Background Reports of kratom (Mitragyna speciosa) use, a medicinal plant widely
found in Southeast Asia, are on the rise in the US. However, the prevalence and …
found in Southeast Asia, are on the rise in the US. However, the prevalence and …
[HTML][HTML] The chemical and pharmacological properties of mitragynine and its diastereomers: an insight review
T Karunakaran, KZ Ngew, AAD Zailan… - Frontiers in …, 2022 - frontiersin.org
Mitragynine, is a naturally occurring indole alkaloid that can be isolated from the leaves of a
psychoactive medicinal plant. Mitragyna speciosa, also known as kratom, is found to …
psychoactive medicinal plant. Mitragyna speciosa, also known as kratom, is found to …
Analgesic opioid ligand discovery based on nonmorphinan scaffolds derived from natural sources
Strong opioid analgesics, including morphine, are the mainstays for treating moderate to
severe acute pain and alleviating chronic cancer pain. However, opioid-related adverse …
severe acute pain and alleviating chronic cancer pain. However, opioid-related adverse …