Non-coding RNAs do not encode proteins and regulate various oncological processes. They
are also important potential cancer diagnostic and prognostic biomarkers. Bioinformatics …

Single-cell RNA sequencing (scRNA-seq), a technology that analyzes transcriptomes of
complex tissues at single-cell levels, can identify differential gene expression and epigenetic …

Immune checkpoint blockade targeting PD-1/PD-L1 has promising therapeutic efficacy in a
variety of tumors, but resistance during treatment is a major issue. In this review, we describe …

The successful treatment of human cancers by immunotherapy has been made possible by
breakthroughs in the discovery of immune checkpoint regulators, including CTLA-4 and PD …

Thyroid cancer is the most prevalent endocrine tumor and its incidence is fast-growing
worldwide in recent years. Differentiated thyroid cancer (DTC) is the most common …

Long noncoding RNA (lncRNA) have emerged as crucial regulators for a myriad of
biological processes, and perturbations in their cellular expression levels have often been …

Mounting evidence has revealed that the therapeutic efficacy of immunotherapies is
restricted to a small portion of cancer patients. A deeper understanding of how metabolic …

Epstein‐Barr virus (EBV) is a tumorigenic virus that can cause various human malignancies
such as nasopharyngeal carcinoma (NPC) and gastric cancer (GC). EBV encodes 44 …

ATP and other nucleoside phosphates have specific receptors named purinergic receptors.
Purinergic receptors and ectonucleotidases regulate various signaling pathways that play a …

BRAFV600E mutation is highly prevalent in patients with papillary thyroid carcinoma (PTC),
and TERT promoter (TERTp) mutation is strongly associated with cancer‐related mortality …