Inflammasomes are multiprotein complexes that critically control different aspects of innate
and adaptive immunity. Among them we could highlight the release of pro-inflammatory …

Familial Mediterranean fever (FMF) is the most common monogenic periodic fever syndrome
and characterized by recurrent episodes of fever, serositis, arthritis, dermal manifestations …

Abstract Background Familial Mediterranean fever, mevalonate kinase deficiency (also
known as the hyperimmunoglobulinemia D syndrome), and the tumor necrosis factor …

Familial Mediterranean fever (FMF) is the most common monogenic autoinflammatory
disease (AID) affecting mainly the ethnic groups originating from Mediterranean basin. The …

Summary Familial Mediterranean Fever (FMF) is the oldest and the most frequent of all
described hereditary periodic fever syndromes. The populations originating from …

Abstract Background Familial Mediterranean Fever (FMF) is a hereditary autoinflammatory
syndrome characterized by recurrent serositis or arthritis attacks and, in some patients …

Autoinflammatory diseases (AIDs) represent a rare and heterogeneous group of disorders
characterized by recurrent episodes of inflammation and a broad range of clinical …

In 2002, intracellular protein complexes known as the inflammasomes were discovered and
were shown to have a crucial role in the sensing of intracellular pathogen-and danger …

Periodic fever syndromes are autoinflammatory diseases. The majority present in infancy or
childhood and are characterised by recurrent episodes of fever and systemic inflammation …

Monogenic autoinflammatory diseases are rare conditions caused by genetic abnormalities
affecting the innate immunity. Previous therapeutic strategies had been mainly based on …