Fluorinated pyrimidines and their nucleosides

C Heidelberger, PV Danenberg… - Adv Enzymol Relat …, 1983 - books.google.com
FU, 5-fluorouracil; FUR, 5-fluorouridine; FUMP, 5-fluorouridine-5'-monophosphate; FUDP, 5-
fluorouridine-5'-diphosphate; FUTP, 5-fluorouridine-5'-triphosphate; FUdR, 5-fluoro-2' …

Enzymes in organic synthesis: Application to the problems of carbohydrate recognition (part 2)

CH Wong, RL Halcomb, Y Ichikawa… - … International Edition in …, 1995 - Wiley Online Library
Recognition of carbohydrates by proteins and nucleic acids is highly specific, but the
dissociation constants are relatively high (generally in the mm to high μm range) because of …

[PDF][PDF] Chemistry of Natural Products

SV Bhat, BA Nagasampagi, M Sivakumar - 2005 - 13.235.221.237
Initial formation of deoxybenzoin 3 from phenyl acetic acid 1 and phenol 2 in the presence of
BF,. Et, O followed by its treatment at mom temperature with N, N'-dimethyl …

One among millions: The chemical space of nucleic acid-like molecules

HJ Cleaves, C Butch, PB Burger… - Journal of Chemical …, 2019 - ACS Publications
Biology encodes hereditary information in DNA and RNA, which are finely tuned to their
biological functions and modes of biological production. The central role of nucleic acids in …

Antiviral screening identifies adenosine analogs targeting the endogenous dsRNA Leishmania RNA virus 1 (LRV1) pathogenicity factor

FM Kuhlmann, JI Robinson… - Proceedings of the …, 2017 - National Acad Sciences
The endogenous double-stranded RNA (dsRNA) virus Leishmaniavirus (LRV1) has been
implicated as a pathogenicity factor for leishmaniasis in rodent models and human disease …

Molecular structure of free canonical 2′-deoxyribonucleosides: a density functional study

OV Shishkin, A Pelmenschikov, DM Hovorun… - Journal of Molecular …, 2000 - Elsevier
The molecular structure of isolated canonical 2′-deoxyrinobucleosides was calculated
using the density functional theory. It was demonstrated that the geometry of the base unit …

A facile enzymatic synthesis of 5'-(3-sn-phosphatidyl) nucleosides and their antileukemic activities

S SHUTO, H ITOH, S UEDA, S IMAMURA… - Chemical and …, 1988 - jstage.jst.go.jp
抄録 Phospholipase D from Streptomyces effectively catalyzed the transfer reaction of the
phosphatidyl residue from 3-sn-phosphatidylcholine to the 5'-hydroxyl group of nuclesides in …

Facile preparation of C-glycosylbarbiturates and C-glycosylbarbituric acids

MA Gonzalez, JLJ Requejo, JCP Albarran… - Carbohydrate …, 1986 - Elsevier
A general method for the synthesis of pyrimidine C-nucleosides involves a one-step reaction
of aldohexoses and aldopentoses with barbituric acids. Thus, 2-amino-2-deoxy-d-glucose …

Uracil analogues of the acyclonucleoside 9-[[2-hydroxy-1-(hydroxymethyl) ethoxy]-methyl] guanine (BIOLF-62)

KK Ogilvie, RG Hamilton, MF Gillen… - Canadian journal of …, 1984 - cdnsciencepub.com
Uracil analogues of the acyclonucleoside 9-[[2-hydroxy-1-(hydroxymethyl)ethoxy]- methyl]guanine
(BIOLF-62) Page 1 Uracil analogues of the acyclonucleoside 9-[[2-hydroxy-1-(hydroxymethy1)ethoxylmethyllguanine …

Nucleoside synthesis mediated by glycosyl transferring enzymes

AK Prasad, S Trikha, VS Parmar - Bioorganic Chemistry, 1999 - Elsevier
In recent years, enzymatic methodology has become a standard technique for the synthesis
of a wide variety of enantiomerically pure precursors and target molecules. Reports on …