[PDF][PDF] Circuit mechanisms of Parkinson's disease

MM McGregor, AB Nelson - Neuron, 2019 - cell.com
Parkinson's disease (PD) is a complex, multi-system neurodegenerative disorder. The
second most common neurodegenerative disorder after Alzheimer's disease, it affects …

[HTML][HTML] Understanding the role of sensorimotor beta oscillations

J Barone, HE Rossiter - Frontiers in systems neuroscience, 2021 - frontiersin.org
Beta oscillations have been predominantly observed in sensorimotor cortices and basal
ganglia structures and they are thought to be involved in somatosensory processing and …

Beyond the status quo: a role for beta oscillations in endogenous content (re) activation

B Spitzer, S Haegens - eneuro, 2017 - eneuro.org
Among the rhythms of the brain, oscillations in the beta frequency range (∼ 13–30 Hz) have
been considered the most enigmatic. Traditionally associated with sensorimotor functions …

Mechanisms of deep brain stimulation

TM Herrington, JJ Cheng… - Journal of …, 2016 - journals.physiology.org
Deep brain stimulation (DBS) is widely used for the treatment of movement disorders
including Parkinson's disease, essential tremor, and dystonia and, to a lesser extent, certain …

Neural mechanisms of transient neocortical beta rhythms: Converging evidence from humans, computational modeling, monkeys, and mice

MA Sherman, S Lee, R Law… - Proceedings of the …, 2016 - National Acad Sciences
Human neocortical 15–29-Hz beta oscillations are strong predictors of perceptual and motor
performance. However, the mechanistic origin of beta in vivo is unknown, hindering …

Exaggerated phase–amplitude coupling in the primary motor cortex in Parkinson disease

C De Hemptinne… - Proceedings of the …, 2013 - National Acad Sciences
An important mechanism for large-scale interactions between cortical areas involves
coupling between the phase and the amplitude of different brain rhythms. Could basal …

Emerging evidence for astrocyte dysfunction in schizophrenia

EC de Oliveira Figueiredo, C Calì, F Petrelli, P Bezzi - Glia, 2022 - Wiley Online Library
Schizophrenia is a complex, chronic mental health disorder whose heterogeneous genetic
and neurobiological background influences early brain development, and whose precise …

Neurosystems: brain rhythms and cognitive processing

J Cannon, MM McCarthy, S Lee, J Lee… - European Journal of …, 2014 - Wiley Online Library
Neuronal rhythms are ubiquitous features of brain dynamics, and are highly correlated with
cognitive processing. However, the relationship between the physiological mechanisms …

The globus pallidus orchestrates abnormal network dynamics in a model of Parkinsonism

B Crompe, A Aristieta, A Leblois, S Elsherbiny… - Nature …, 2020 - nature.com
The dynamical properties of cortico-basal ganglia (CBG) circuits are dramatically altered
following the loss of dopamine in Parkinson's disease (PD). The neural circuit dysfunctions …

Non-invasive suppression of essential tremor via phase-locked disruption of its temporal coherence

SR Schreglmann, D Wang, RL Peach, J Li… - Nature …, 2021 - nature.com
Aberrant neural oscillations hallmark numerous brain disorders. Here, we first report a
method to track the phase of neural oscillations in real-time via endpoint-corrected Hilbert …