EASL clinical practice guidelines: management of hepatocellular carcinoma

PR Galle, A Forner, JM Llovet, V Mazzaferro… - Journal of …, 2018 - Elsevier
Liver cancer is the fifth most common cancer and the second most frequent cause of cancer-
related death globally. Hepatocellular carcinoma represents about 90% of primary liver …

The immunology of hepatocellular carcinoma

M Ringelhan, D Pfister, T O'Connor, E Pikarsky… - Nature …, 2018 - nature.com
In contrast to most other malignancies, hepatocellular carcinoma (HCC), which accounts for
approximately 90% of primary liver cancers, arises almost exclusively in the setting of …

Guidelines for diagnosis and treatment of primary liver cancer in China (2017 Edition)

J Zhou, HC Sun, Z Wang, WM Cong, JH Wang… - Liver cancer, 2018 - karger.com
Abstract Background: Hepatocellular carcinoma (HCC)(about 85–90% of primary liver
cancer) is particularly prevalent in China because of the high prevalence of chronic hepatitis …

[HTML][HTML] From bench to bed: the tumor immune microenvironment and current immunotherapeutic strategies for hepatocellular carcinoma

Y Fu, S Liu, S Zeng, H Shen - Journal of Experimental & Clinical Cancer …, 2019 - Springer
Hepatocellular carcinoma (HCC) ranks the most common primary liver malignancy and the
third leading cause of tumor-related mortality worldwide. Unfortunately, despite advances in …

[HTML][HTML] Immunotherapy for hepatocellular carcinoma: current status and future prospects

Z Liu, X Liu, J Liang, Y Liu, X Hou, M Zhang… - Frontiers in …, 2021 - frontiersin.org
Hepatocellular carcinoma (HCC) is the most prevalent primary liver cancer with poor
prognosis. Surgery, chemotherapy, and radiofrequency ablation are three conventional …

[HTML][HTML] Cell therapy: types, regulation, and clinical benefits

AEH El-Kadiry, M Rafei, R Shammaa - Frontiers in Medicine, 2021 - frontiersin.org
Cell therapy practices date back to the 19th century and continue to expand on
investigational and investment grounds. Cell therapy includes stem cell-and non–stem cell …

Risk factors and prevention of hepatocellular carcinoma in the era of precision medicine

N Fujiwara, SL Friedman, N Goossens, Y Hoshida - Journal of hepatology, 2018 - Elsevier
Patients who develop chronic fibrotic liver disease, caused by viral or metabolic aetiologies,
are at a high risk of developing hepatocellular carcinoma (HCC). Even after complete HCC …

[HTML][HTML] 2018 Korean Liver Cancer Association–National Cancer Center Korea practice guidelines for the management of hepatocellular carcinoma

Korean Liver Cancer Association - Gut and liver, 2019 - ncbi.nlm.nih.gov
Hepatocellular carcinoma (HCC) is the fifth most common cancer globally and the fourth
most common cancer in men in Korea, where the prevalence of chronic hepatitis B infection …

[HTML][HTML] Immune-based therapies for hepatocellular carcinoma

DJ Pinato, N Guerra, P Fessas, R Murphy, T Mineo… - Oncogene, 2020 - nature.com
Hepatocellular carcinoma (HCC) is the third most frequent cause of cancer-related death.
The immune-rich contexture of the HCC microenvironment makes this tumour an appealing …

IMbrave 050: a Phase III trial of atezolizumab plus bevacizumab in high-risk hepatocellular carcinoma after curative resection or ablation

SP Hack, J Spahn, M Chen, AL Cheng, A Kaseb… - Future …, 2020 - Future Medicine
Hepatocellular carcinoma recurs in 70–80% of cases following potentially curative resection
or ablation and the immune component of the liver microenvironment plays a key role in …