Neoadjuvant and adjuvant systemic therapies in loco-regional treatments for hepatocellular carcinoma: are we at the dawn of a new era?
Simple Summary The treatment of hepatocellular carcinoma is burdened by an
unacceptable recurrence rate after loco-regional treatment. Unlike all other solid tumors, no …
unacceptable recurrence rate after loco-regional treatment. Unlike all other solid tumors, no …
Novel adjuvant dendritic cell therapy with transfection of heat-shock protein 70 messenger RNA for patients with hepatocellular carcinoma: a phase I/II prospective …
HM Matsui, S Hazama, M Nakajima, M Xu… - Cancer Immunology …, 2021 - Springer
Introduction A proteomic analysis of hepatocellular carcinoma (HCC) has revealed that Heat
Shock Protein 70 (HSP70) is among the cancer antigen proteins of HCC. Moreover, we …
Shock Protein 70 (HSP70) is among the cancer antigen proteins of HCC. Moreover, we …
Adoptive cell transfer therapy for hepatocellular carcinoma
R Zhang, Z Zhang, Z Liu, D Wei, X Wu, H Bian… - Frontiers of …, 2019 - Springer
Hepatocellular carcinoma (HCC) is one of the most common cancers worldwide. This
malignancy is associated with poor prognosis and high mortality. Novel approaches for …
malignancy is associated with poor prognosis and high mortality. Novel approaches for …
CXCL2/10/12/14 are prognostic biomarkers and correlated with immune infiltration in hepatocellular carcinoma
T Lin, E Zhang, P Mai, Y Zhang, X Chen… - Bioscience …, 2021 - portlandpress.com
Background: CxC motif chemokine ligands (CXCLs) are critical regulators of cancer
immunity and angiogenesis, which affect disease progression and treatment responses. The …
immunity and angiogenesis, which affect disease progression and treatment responses. The …
Immunotherapy in hepatocellular carcinoma: is there a light at the end of the tunnel?
Hepatocellular carcinoma (HCC) is the most common primary liver cancer with dismal
prognosis when diagnosed at advanced stages. Surgical resection of the primary tumor or …
prognosis when diagnosed at advanced stages. Surgical resection of the primary tumor or …
Impact and novel perspective of immune checkpoint inhibitors in patients with early and intermediate stage HCC
L Marzi, A Mega, S Gitto, F Pelizzaro, A Seeber… - Cancers, 2022 - mdpi.com
Simple Summary The prognostic evaluation and therapeutic management of
hepatocarcinoma (HCC) is based on the Barcelona Liver Cancer Clinic (BCLC). In the past …
hepatocarcinoma (HCC) is based on the Barcelona Liver Cancer Clinic (BCLC). In the past …
Adjuvant and neoadjuvant therapies for hepatocellular carcinoma
Immune-oncology based regimens have shown efficacy in advanced hepatocellular
carcinoma and have been implemented as standard of care as first line therapy. Their …
carcinoma and have been implemented as standard of care as first line therapy. Their …
Activity of IL-12/15/18 primed natural killer cells against hepatocellular carcinoma
Background Hepatocellular carcinoma (HCC) is common, but remains difficult to treat.
Natural killer (NK) cells are cells of the innate immune system that have potent anti-cancer …
Natural killer (NK) cells are cells of the innate immune system that have potent anti-cancer …
Emerging treatment modalities for systemic therapy in hepatocellular carcinoma
X Qing, W Xu, J Zong, X Du, H Peng, Y Zhang - Biomarker Research, 2021 - Springer
Hepatocellular carcinoma (HCC) has long been a major global clinical problem as one of
the most common malignant tumours with a high rate of recurrence and mortality. Although …
the most common malignant tumours with a high rate of recurrence and mortality. Although …
PD-L1 expression as a predictive biomarker for cytokine-induced killer cell immunotherapy in patients with hepatocellular carcinoma
CL Chen, QZ Pan, JJ Zhao, Y Wang, YQ Li… - …, 2016 - Taylor & Francis
Cytokine-induced killer (CIK) cell immunotherapy represents an effective treatment strategy
for treating hepatocellular carcinoma (HCC). However, the therapeutic benefits of CIK cell …
for treating hepatocellular carcinoma (HCC). However, the therapeutic benefits of CIK cell …