Host immunity is an important but poorly understood determinant of antimalarial efficacy,
influencing the outcome of prevention and treatment trials. Variations in host immunity might …

Abstract In this review, Mike Doenhoff and colleagues discuss the immune dependency of
chemotherapy and the consequences for drug resistance. They also consider the …

An assessment was done in Tanzania to determine the extent to which the primary health
care services have contributed to reducing the burden of malaria since the system was …

Serial in vitro and in vivo tests for chloroquine sensitivity of Plasmodium falciparum were
carried out from 1979 to 1982 in an area of E. Africa where chemosuppression with …

From the numerous reports that have appeared over the last decade about the failure of
chloroquine to produce radical cure of infection with Plasmodium falciparum it is clear that …

There are comparatively few studies concerned specifically with chemotherapy of parasitic
infections and its relationship with the immune status of the host being treated. In one sense …

The sensitivity of Plasmodium falciparum to chloroquine was tested in Muheza, Pangani,
Tanga and Korogwe districts in north-eastern Tanzania by applying both in vivo and in vitro …

Remember that, as it is monstrous to be surprised at a fig-tree bearing figs, so also is it to be
surprised at the Universe bearing its own particular crop. Likewise it is monstrous for a …

It is perhaps not surprising that few planned studies on the interactions between
chemotherapy of malaria and the immune status of infected individuals or animals have …

Since the detection of strains of Plasmodium falci-parum resistant to drugs of the 4-
aminoquinoline group in South America and South-East Asia, awareness of the problem has …