Pancreatic cancer (PC) remains one of the worst cancers, with almost uniform lethality. PC
risk is associated with westernized diet, tobacco, alcohol, obesity, chronic pancreatitis, and …

Recent development of genetically engineered mouse models (GEMs) for pancreatic cancer
(PC) that recapitulates human disease progression has helped to identify new strategies to …

Abstract Cyclooxygenase-2 (COX-2), 5-Lipoxygenase (5-LOX), and epidermal growth factor
receptor (EGRF) are over-expressed in human pancreatic ductal adenocarcinoma (PDAC) …

Pancreatic ductal adenocarcinoma (PDAC) is one of the deadliest major cancers, with a five
year survival rate of less than 8%. With current therapies only giving rise to modest life …

Pancreatic cancers are currently the fourth leading cause of cancer-related death and new
therapies are desperately needed. The most common pancreatic cancer is pancreatic ductal …

Objective: Rare disease Background: Hyperammonemic encephalopathy is a potentially
fatal condition that may progress to irreversible neuronal damage and is usually associated …

There remains intense interest in tractable approaches to target or silence the KRAS
oncoprotein as a rational therapeutic strategy to attack pancreatic ductal adenocarcinoma …

Idiopathic pulmonary fibrosis is a progressive, fatal lung disease with poor survival. The
advances made in deciphering this disease have led to the approval of different antifibrotic …

To explore the function of ornithine decarboxylase in esophageal squamous cell carcinoma
progression and test the effectiveness of anti-ornithine decarboxylase therapy for …

Spermine, spermidine and putrescine polyamines are naturally occurring ubiquitous
positively charged amines and are essential metabolites for biological functions in our life …