A mathematical model that integrates cardiac electrophysiology, mechanics, and fluid dynamics: Application to the human left heart
We propose a mathematical and numerical model for the simulation of the heart function that
couples cardiac electrophysiology, active and passive mechanics and hemodynamics, and …
couples cardiac electrophysiology, active and passive mechanics and hemodynamics, and …
[HTML][HTML] Electro-mechanical whole-heart digital twins: a fully coupled multi-physics approach
T Gerach, S Schuler, J Fröhlich, L Lindner… - Mathematics, 2021 - mdpi.com
Mathematical models of the human heart are evolving to become a cornerstone of precision
medicine and support clinical decision making by providing a powerful tool to understand …
medicine and support clinical decision making by providing a powerful tool to understand …
Polygonal surface processing and mesh generation tools for the numerical simulation of the cardiac function
M Fedele, A Quarteroni - International Journal for Numerical …, 2021 - Wiley Online Library
In order to simulate the cardiac function for a patient‐specific geometry, the generation of the
computational mesh is crucially important. In practice, the input is typically a set of …
computational mesh is crucially important. In practice, the input is typically a set of …
[HTML][HTML] Simulating ventricular systolic motion in a four-chamber heart model with spatially varying robin boundary conditions to model the effect of the pericardium
The pericardium affects cardiac motion by limiting epicardial displacement normal to the
surface. In computational studies, it is important for the model to replicate realistic motion, as …
surface. In computational studies, it is important for the model to replicate realistic motion, as …
A geometric multiscale model for the numerical simulation of blood flow in the human left heart
We present a new computational model for the numerical simulation of blood flow in the
human left heart. To this aim, we use the Navier-Stokes equations in an Arbitrary Lagrangian …
human left heart. To this aim, we use the Navier-Stokes equations in an Arbitrary Lagrangian …
[HTML][HTML] An electromechanics-driven fluid dynamics model for the simulation of the whole human heart
We introduce a multiphysics and geometric multiscale computational model, suitable to
describe the hemodynamics of the whole human heart, driven by a four-chamber …
describe the hemodynamics of the whole human heart, driven by a four-chamber …
Data integration for the numerical simulation of cardiac electrophysiology
The increasing availability of extensive and accurate clinical data is rapidly shaping
cardiovascular care by improving the understanding of physiological and pathological …
cardiovascular care by improving the understanding of physiological and pathological …
[HTML][HTML] Automating image-based mesh generation and manipulation tasks in cardiac modeling workflows using meshtool
Advanced cardiac modeling studies rely on the ability to generate and functionalize
personalized in silico models from tomographic multi-label image stacks. Eventually, this is …
personalized in silico models from tomographic multi-label image stacks. Eventually, this is …
[HTML][HTML] A computationally efficient physiologically comprehensive 3D–0D closed-loop model of the heart and circulation
Computer models of cardiac electro-mechanics (EM) show promise as an effective means
for the quantitative analysis of clinical data and, potentially, for predicting therapeutic …
for the quantitative analysis of clinical data and, potentially, for predicting therapeutic …
Recapitulating cardiac structure and function in vitro from simple to complex engineering
Cardiac tissue engineering aims to generate in vivo-like functional tissue for the study of
cardiac development, homeostasis, and regeneration. Since the heart is composed of …
cardiac development, homeostasis, and regeneration. Since the heart is composed of …