Precision oncology continues to challenge the “one-size-fits-all” dogma. Under the precision
oncology banner, cancer patients are screened for molecular tumor alterations that predict …

Angiogenesis is the process through which new blood vessels are formed from pre-existing
ones. Exosomes are involved in angiogenesis in cancer progression by transporting …

Microfluidic lumen-based systems are microscale models that recapitulate the anatomy and
physiology of tubular organs. These technologies can mimic human pathophysiology and …

The extracellular matrix (ECM) composition greatly influences cancer progression, leading
to differential invasion, migration, and metastatic potential. In breast cancer, ECM …

Cancer is a leading cause of death across the world and continues to increase in incidence.
Despite years of research, multiple tumors (eg, glioblastoma, pancreatic cancer) still have …

Lymphatic vessels (LVs) have been suggested as a preferential conduit for metastatic
progression in breast cancer, where a correlation between the occurrence of lymph node …

To accelerate the discovery of anti-cancer drugs, there is an urgent need to establish an
inexpensive and simple preclinical model that can simulate the tumor microenvironment and …

The vascular system is integral for maintaining organ‐specific functions and homeostasis.
Dysregulation in vascular architecture and function can lead to various chronic or acute …

Renal cell carcinomas are common genitourinary tumors characterized by high
vascularization and strong reliance on glycolysis. Despite the many available therapies for …

Cancer can disrupt the microenvironments and mechanical homeostatic actions in multiple
scales from large tissue modification to altered cellular signaling pathway in …