Despite the advantages of microfluidic system in drug screening, vascular systems
responsible for the transport of drugs and nutrients have been hardly considered in the …

In breast cancer development, crosstalk between mammary epithelial cells and neighboring
vascular endothelial cells is critical to understanding tumor progression and metastasis, but …

The prostate tumor microenvironment (TME) is strongly immunosuppressive; it is largely
driven by alteration in cell phenotypes (ie tumor-associated macrophages and exhausted …

Fibrillar collagens are prominent extracellular matrix (ECM) components, and their topology
changes have been shown to be associated with the progression of a wide range of …

Organs-on-chips (OOC) are widely seen as being the next generation in vitro models able to
accurately recreate the biochemical-physical cues of the cellular microenvironment found in …

The determination of factors associated with progression of cervical cancer is important, both
for a recurrence risk assessment and for determining optimal treatment tactics. Previously …

The last decade has seen many exciting technological breakthroughs that greatly expanded
the toolboxes for biological and biomedical research, yet few have had more impact than …

Gastric cancer (GC) remains a serious oncological problem, ranking third in the structure of
mortality from malignant neoplasms. Improving treatment outcomes for this pathology largely …

The mass use of biological agents for pharmaceutical purposes started with the
development and distribution of vaccines, followed by the industrial production of antibiotics …

For a long time, cancer research has been at the forefront of scientific and medical study.
Cancer is a chronic illness that results from alterations or mutations in genes. In the year …