Doxorubicin—an agent with multiple mechanisms of anticancer activity

M Kciuk, A Gielecińska, S Mujwar, D Kołat… - Cells, 2023 - mdpi.com
Doxorubicin (DOX) constitutes the major constituent of anti-cancer treatment regimens
currently in clinical use. However, the precise mechanisms of DOX's action are not fully …

[HTML][HTML] Evaluation of the association of chronic inflammation and cancer: Insights and implications

M Nigam, AP Mishra, VK Deb, DB Dimri, V Tiwari… - Biomedicine & …, 2023 - Elsevier
Among the most extensively researched processes in the development and treatment of
cancer is inflammatory condition. Although acute inflammation is essential for the wound …

The applications of nanozymes in cancer therapy: based on regulating pyroptosis, ferroptosis and autophagy of tumor cells

Y Zhang, W Yu, M Chen, B Zhang, L Zhang, P Li - Nanoscale, 2023 - pubs.rsc.org
Nanozymes are nanomaterials with catalytic properties similar to those of natural enzymes,
and they have recently been collectively identified as a class of innovative artificial enzymes …

[HTML][HTML] Ferroptosis in colorectal cancer: Potential mechanisms and effective therapeutic targets

Y Wang, Z Zhang, W Sun, J Zhang, Q Xu, X Zhou… - Biomedicine & …, 2022 - Elsevier
Colorectal cancer (CRC) is a common malignant tumor characterized by unchecked division
and survival of abnormal cells in the colon or rectum with high morbidity and mortality …

Cardamonin alleviates chondrocytes inflammation and cartilage degradation of osteoarthritis by inhibiting ferroptosis via p53 pathway

Z Gong, Y Wang, L Li, X Li, B Qiu, Y Hu - Food and Chemical Toxicology, 2023 - Elsevier
Osteoarthritis (OA) is a common degenerative joint disease, mainly presented by the
deterioration of articular cartilage. Amounts of data demonstrated this deterioration is …

Ferroptosis and senescence: A systematic review

D Coradduzza, A Congiargiu, Z Chen, A Zinellu… - International Journal of …, 2023 - mdpi.com
Senescence is a cellular aging process in all multicellular organisms. It is characterized by a
decay in cellular functions and proliferation, resulting in increased cellular damage and …

Chronic arsenic exposure induces ferroptosis via enhancing ferritinophagy in chicken livers

L Yu, Z Lv, S Li, H Jiang, B Han, X Zheng, Y Liu… - Science of The Total …, 2023 - Elsevier
Arsenic (As) is a well-known pollutant in the environment, whose contamination in
groundwater is a serious threat to animals and humans. Ferroptosis, a form of cell death …

[HTML][HTML] Medicinal and mechanistic overview of artemisinin in the treatment of human diseases

AM Posadino, R Giordo, G Pintus… - Biomedicine & …, 2023 - Elsevier
Artemisinin (ART) is a bioactive compound isolated from the plant Artemisia annua and has
been traditionally used to treat conditions such as malaria, cancer, viral infections, bacterial …

MiR-148a-3p Promotes Colorectal Cancer Cell Ferroptosis by Targeting SLC7A11

E Martino, A Balestrieri, F Aragona, G Bifulco, L Mele… - Cancers, 2023 - mdpi.com
Simple Summary The role of miR-148a-3p in colorectal cancer (CRC) is still debated. In this
study, the in vitro antineoplastic effect of miR-148a-3p overexpression in the CRC model is …

[PDF][PDF] Ferroptosis in neurodegenerative diseases: inhibitors as promising candidate mitigators.

RF Zhang, M Zeng, N Lv, LM Wang… - European Review for …, 2023 - europeanreview.org
Ferroptosis is a new form of iron-dependent programmed cell death, characterized by
intracellular iron overload and lipid peroxidation. Several studies have revealed that …